The occurrence of FA and carbonyl compounds (acetaldehyde, acrolein, EC, formaldehyde and furfural) was studied in this research with the objective of verifying, for the first time, the risk of exposure to these compounds through consumption of sparkling wines.
But if you drink too much too quickly, the liver can't keep up and the concentration of toxic acetaldehyde in your system will trigger the unpleasant symptoms of a pulsating headache, dry mouth and nausea.
Therefore, this study aimed to analyze the mechanism of action of alpha mangostin on acetaldehyde induced liver fibrosis model on TGF-[beta] and ERK 1/2 pathways.
Previous in vitro and in vivo studies have indicated that the detrimental effects of ethanol in the pancreas is likely due to the toxic effects of ethanol metabolism via the oxidative pathways, generating acetaldehyde metabolites, or via non-oxidative pathways, producing fatty acid ethyl esters.
This result is in agreement with the previous report [17], in which the dehydration of ethanol over acid catalyst was studied and it was found that the products of ethanol dehydration reaction are ethylene (main product), diethyl ether, and acetaldehyde. The ethylene formation is favored by medium to strong acid sites, whereas diethyl ether requires only weak acid sites.