Some of the possible outcomes of SSM include premature termination due to nonsense codon generation or altered protein due to frame-shifted mutation, loss or reduction of accessory proteins
binding, loss or reduction of promoter's activity.
Considering the previously mentioned problems with the accuracy of ASPCR for allelic differentiation, we hypothesized that adding replication accessory proteins
to our reactions would suppress potential false-positive results caused by high amounts of the wild-type allele.
The presence of this accessory protein
was confirmed by SDS-PAGE as a band corresponding to 14 kDa (Fig.
To see whether the yeast contained the enzyme they were looking for, they then isolated the yeast's cellular membranes, which contained the accessory protein
and the candidate protein from soybean, and chemical precursors for isoflavone synthesis.
CSC012-ADC targets the interleukin 1 receptor accessory protein
(IL1RAP), which has been shown to be expressed on leukemic cancer stem cells, but not on normal hematopoietic stem cells.
But HIV has evolved a way to overcome restriction using an accessory protein
called Vif (virion infectivity factor) to degrade the APOBEC proteins and allow the virus to spread.
in viral pathogenesis, the mechanism underlying nuclear transport of HIV-I accessory protein
Vpr, one of the significant agents in AIDS pathogenesis, have been emphasized in the section on basic research.
Other accessory proteins
necessary for efficient translocation of proteins across the inner membrane, such as YidC protein (RWLH02988), trigger factor, ppiase (RWLH04521) and two ORFs for SecY stabilizing membrane protein (RWLH04883, RWLH05233), were identified.