sup] However, sometimes acantholysis
might be minimal or absent.
is the loss of intercellular bridges of cells of spinosum layer which can result in the formation of blisters and ulcers in oral mucosa.
has also been reported (Table 1).
Foldes, E Cottenot: "Subcorneal pustulosis, superficial acantholysis
and monoclonal IgA".
Since the desmosomes are the primary attachment mechanism between keratinocytes, this disease results in acantholysis
in epidermis .
The lesion is characterized by intraepidermal vesicles with acantholysis
and an intact basal layer.
of the filled blisters in non- spinous cell layer with inflamed skin.
Tannic acid induces in vitro acantholysis
of keratinocytes via IL-1 alpha and TNF-alpha.
Tomecki described as "suprabasilar bullae with acantholysis
against a background clinical appearance of moist, macerated plaques.
In addition, you may see acantholysis
of the follicular epithelium," Dr.
The salient histopathological features of PF observed in our study were acantholysis
(100%) and subcorneal bulla (100%).
The histologic hallmark of PV and PF is acantholysis
6) Frozen sections can rapidly differentiate the superficial subgranular acantholysis
in SSSS and the characteristic full-thickness epidermal necrosis and dermal-epidermal separation seen in TEN.
The acantholytic microscopic variant of squamous cell carcinoma is characterized by extensive acantholysis
resulting in pseudoglandular or pseudovascular spaces.