tethers Xist RNA to the inactive X nucleation center.
But animals in which the YY1
protein was "knocked out" in their muscles had no such response to rapamycin - they were protected against the development of diabetes-like symptoms.
The first intron of the porcine [beta]-casein gene contained the putative Oct-1, SRY, YY1
, C/EBP[beta], AP-1, and retroviral TATA box.
The CD30 gene promoter microsatellite binds transcription factor Yin Yang 1 (YY1
) and shows genetic instability in anaplastic large cell lymphoma.
Several host cell transcription factor binding sites and keratinocytes specific enhancers like AP-1, Sp1, NF-1, TEF-1, TEF-2, Oct-1, AP-2, KRF-1, YY1
, STAT3 and glucocorticoid responsive elements have been identified in the upstream regulatory region (URR) of HPV, which determine the cell-type-specific viral gene expression and contribute to the tissue tropism of HPV (20,21).
Kim, "Retroposition and Evolution of the DNA-binding Motifs of YY1
, YY2, and REX1," Nucleic Acids Research 35 (2007): 3442-52.
Wu et al., "MicroRNA-7 is a novel inhibitor of YY1
contributing to colorectal tumorigenesis," Oncogene, vol.
Another crucial myomiR that is currently undergoing scientific studies is miR-29, which is regulated by NF-[kappa]B acting through YY1
and the polycomb group.