xenograft

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Related to Xenografts: Allografts, xenogeneic transplantation
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Synonyms for xenograft

tissue from an animal of one species used as a temporary graft (as in cases of severe burns) on an individual of another species

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Three bone substitutes were used, as follows: one xenograft consisting of deproteinized and lyophilized bovine bone, and two fully alloplastic one based on pure phase beta-tricalcium phosphate (TCP) (>99 %) (alloplastic graft 1) and other based on biphasic calcium phosphate (60 % HA / 40 % beta-TCP) (alloplastic graft 2).
Efficacy of the Ethanol Injection on the Control of Subcutaneous Pancreatic Cancer Cell Mouse Xenografts. During the experiments, one mouse each in the 60% and 80% ethanol groups and two mice in the 95% ethanol group of the subcutaneous xenograft model died, which might have been due to the excessive ethanol dose.
Tissue lysates from HT-29 xenografts were prepared according to a standard protocol using RIPA buffer (according to sample size approx.
The length and width of the xenografts were measured twice per week after tumor formation, and relative tumor volume was calculated using the formula: relative tumor volume = 0.5 x length diameter x short [diameter.sup.2].
Mouse xenografts were harvested at appropriate tumor size with sterile surgical tools.[sup][7],[8],[9] Tumor tissue was minced into tiny pieces with scissors, and the tissue fragments were incubated in collagenase solution (Invitrogen, California, USA) at 37[degrees]C for up to 1 h.
In several studies, the experimental checkpoint inhibitors targeting CTLA-4 and PD-1 depicted anti-tumor activity in traditional xenografts as well as PDX of NSCLC.
It specialises in in vivo pharmacology services, leveraging an extensive collection of more than 400 patient-derived xenograft (PDX) tumor models, as well as a full range of in vitro assays using both commercially available and proprietary PDX-derived cell lines.
Oncotest specialises in in vivo pharmacology services, leveraging an extensive collection of more than 400 patient-derived xenograft tumor models, as well as a range of in vitro assays using both commercially available and proprietary PDX-derived cell lines.
The effect of combined MTE and gefitinib on the growth of NSCLC tumour xenografts
In a separate set of experiments, mice bearing human fetal testis xenografts were dosed with DBP at 0 or 500 mg/kg daily for 3 weeks, after which the xenografted samples underwent the same analyses as those from the rats.
Ki67 staining in tumor xenografts from mice were treated with VPA was significantly lower than that observed for the vehicle control group [Figure 7]e], indicating an in vivo inhibitory effect of VPA treatment on tumor cell proliferation.{Figure 7}
The recovered xenografts were dispersed using fine forceps and 26-gauge needles attached to 1 ml syringes and then cryopreserved until use.
Canadian investigators have reported success with generating high-fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development (Cancer Res.
They cover the form, structure, and features of bone; fracture healing and bone grafting; aspects of cartilage; bone xenografts; transplantation of autologous bone, autologous cartilage and chondrocytes, allogeneic cartilage, and tendons, ligaments, and membranes; bone grafts in spine stabilization; limb saving procedures; tissue banking; and tissue engineering.