High expression of Wilms' tumor
suppressor gene predicts poor prognosis in breast cancer patients.
7 Oji Y, Yano M, Nakano Y, Abeno S, Nakatsuka S-I, Ikeba A, Yasuda T, Fujiwara Y, Takiguchu S, Yamamoto H: Overexpression of the Wilms' tumor
gene WT1 in esophageal cancer.
Adult Wilms' tumor
has well known diagnostic criteria which include: 1) primary renal neoplasm, 2) presence of primitive blastemic spindle or round cell component, 3) formation of abortive tubules or glomerular structures, 4) no area of tumor diagnostic of renal cell carcinoma, 5) pictorial confirmation of histology, and 6) patient age >15 years (2).
Unal, "A case of Wilms' tumor
with spinal cord involvement," Journal of Pediatric Neurology, vol.
In contrast to the vast majority of cases of Wilms' Tumor
in which the appropriate surgical management involves radical nephrectomy, the benign nature of ORTIs makes them amenable to partial nephrectomies.
His past medical history included a right-sided Wilms' tumor
treated with unilateral nephrectomy when he was 2 years old.
DSP-7888 is an investigational cancer peptide vaccine containing peptides that induce Wilms' tumor
gene 1 -specific cytotoxic T lymphocytes and helper T cells, which attack WT1-expressing cancerous cells found in various types of hematologic and solid cancers.
Patient 3 was a 9-year-old male with stage 3 favorable histology Wilms' tumor
who had pulmonary recurrence 13 months after his initial therapy and was treated with 6 cycles of ICE chemotherapy with PBSC support after cycles 3 through 6.
iPS Treatment and Wilms' Tumor
GlobalData's clinical trial report, "Wilms' Tumor
(Nephroblastoma) Global Clinical Trials Review, H1, 2016" provides an overview of Wilms' Tumor
(Nephroblastoma) clinical trials scenario.
Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic analysis of 146 adult and pediatric cases from the National Wilms' Tumor
Study Group Pathology Center.
Identification and analysis of mutations in WTX and WT1 genes in peripheral blood and tumor tissue of children with Wilms' tumor
. Chin Med J 2012;125:1733-9.
Kidney protein profiling of Wilms' tumor
patients by analysis of formalin-fixed paraffin-embedded tissue samples.
or nephroblastoma accounts for more than 95% of all kidney tumors in children.