We conclude that human umbilical cord Wharton's jelly
(hUCWJ) is a superior source for getting high yield Mesenchymal stem cells.
Spontaneous bleeding in the umbilical cord is due to a disruption of the vessel wall through which, in most cases, an extravasation of blood into Wharton's jelly
The search outcomes identified all articles containing the words Wharton's jelly
, umbilical cord, osteogenesis, osteogenic, and bone.
Given this background, we sought to compare the construction of tissue-engineered cartilage scaffolds using Wharton's jelly
ECM (WJECM) with that using articular cartilage ECM (ACECM).
The high activity of telomerase found in MSCs from bovine fetuses from Wharton's jelly
(CARDOSO et al., 2012) allowed to state that this cell type is poorly differentiated.
Isolation, culture and characterisation of fibroblast-like cells derived from the Wharton's jelly
portion of human umbilical cord.
In GDM group, light microscopy showed erosion of the endothelium and complete rupture of the umbilical vessels resulting in extravasation of blood within Wharton's jelly
. The umbilical vein was grossly dilated and thin walled.
The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly
in the treatment of rat liver fibrosis.
showed that amniotic membrane contains mesenchymal stem cells with osteogenic and adipogenic differentiation potential.9 MSCs have been isolated from other parts of the placenta including the Wharton's jelly10 amniotic fluid11 chorionic membrane.12 Wharton's Jelly
is the primitive connective tissue of the umbilical cord trapped in the connective tissue.10
However, the umbilical cord Wharton's jelly
cells  and bone marrow mesenchymal cells  were used frequently, and the adipose mesenchymal stem cells were selected in this research not only because of extensive sources, but also because of the fact that the fat tissue plays an important role in reepithelialization of damaged tissue and reconstruction of skin appendage.
Giampaolo et al., "Induction of dopaminergic neurons From human Wharton's Jelly
mesenchymal stem cell by forskolin," Journal of Cellular Physiology, vol.
Antenatally the differential diagnosis of patent urachus includes pseudo-cyst (degeneration of Wharton's jelly
), allantoic cyst , omphalo-mesentric duct cysts, anterior abdominal wall defects, vascular lesions of the umbilical cord and bladder exstrophy.
While the initial foray of Stempeutics is in bone marrow derived MSCs, Stempeutics is investing on its R&D programs to bring out some innovative products in the near future based on MSCs derived from Wharton's Jelly
, Adipose Tissues and Dental Pulp.
The cells are obtained from the gelatinous material in the cord known as Wharton's jelly
and from blood vessel walls.
While umbilical cord blood is now routinely procured, the material, called Wharton's Jelly
, is routinely discarded at birth.