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Related to Waardenburg's syndrome: Waardenburg syndrome type 1, Waardenburg syndrome type 2
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Twelve of these patients met the diagnostic criteria for type I Waardenburg's syndrome as proposed by Farrer et al, [11] and 11 were diagnosed with type II syndrome, as described by Liu et al.
Newton's data on 79 patients, who belonged to 10 families with Waardenburg's syndrome, were not affected by the reasons that these patients had visited their physician.
In a small study published jointly, Liu and Newton reported the detection of a notch between 1,000 and 3,000 Hz in the DP-grams of seven of eight (88%) normal-hearing patients with Waardenburg's syndrome. [10] The notch was present in all five of their type II patients and in two of their three type I patients.
Waardenburg's syndrome accounts for 2 to 3 percent of the 1 million cases of congenital deafness in the United States, according to the National Institute on Deafness and Other Communication Disorders in Bethesda, Md.
Waardenburg's syndrome -- first described in 1951 by Dutch physician Petrus J.
Although her initial experiments suggest that Splotch mice are not deaf, she says the mice may still be good animal models of Waardenburg's syndrome.