The study results indicated substantially lower systemic estradiol exposure of TX 12-004-HR when compared to Vagifem
vaginal tablets provide extremely low doses of estradiol for local estrogen therapy.
For example, the following topical products containing estrogen - Premarin vaginal cream and Vagifem
tablets - are labeled to warn of the increased risks of heart disease, heart attack, stroke, and uterine and breast cancer in postmenopausal women.
Fourteen women were using one vaginal estrogen tablet (Vagifem
) inserted twice weekly, and 10 were using the vaginal estradiol ring (Estring), inserted every 3 months.
The Danish pharmaceuticals company Novo Nordisk A/S said today (30 May) that it was disputing Pfizer's right to terminate a licence agreement under which Pfizer markets Novo Nordisk's portfolio of hormone replacement therapy products Activella and Vagifem
in the US.
And a vaginal tablet (Vagifem
) containing estradiol, a type of estrogen, is available by prescription for vaginal dryness.
Vaginal estrogen creams and tablets (Vagifem
10 [micro]g per tablet) are often started daily for 2 weeks for a "priming dose" then dosed twice per week.
M2 PHARMA-August 23, 2010-Novo Nordisk signs exclusive agreement with Upsher-Smith Laboratories to market Vagifem
10 mcg(C)2010 M2 COMMUNICATIONS