Data from the Neonatal Research Network VLBW
registry (National Institute of Child Health and Human Development, USA) show an overall IVH prevalence of ~29% and a 22% prevalence of severe IVH between 1997 and 2002.
NICUs and VLBW
births, the authors developed categories of NICUs based on the percent of black VLBW
Differences between groups (VLBW
cases, controls; metabolic syndrome present, absent) were determined using the Student i-test or Fisher exact test as appropriate.
Moreover, it has been proven that the information and the advices given to the mothers of VLBW
on the benefits and on the practices of the breastfeeding, do not represent an additional risk factor for the maternal stress but they become a way to make women (who had a premature or difficult delivery) aware and coprotagonists of the care of their children, even when the clinical conditions of the newborns are critical [42, 43].
Despite the referral protocol in place, many high-risk VLBW
and ELBW deliveries still do not take place at GSH.
The study showed that parents of VP and VLBW
babies were confronted with more challenging situations during their children's life: their child's different start in neonatal intensive care, a much higher rate of disability (e.g.
The following variables were taken into consideration: MDI, PDI, and BRS, according to the BSID-II (as outcome measures); and days of gestational age (GA), birth weight (BW), categories of preterm infants on the basis of BW (VLBW
and ELBW), categories on the basis of size versus GA (appropriate for GA, AGA, and small for G, SGA), head circumference (HC), 1-minute Apgar score (1'-AS) and 5-minute Apgar score (5'-AS), levels of severity on the basis of cranial ultrasound (CU) reports, presence or absence of bronchopulmonary dysplasia (BPD), and days of mechanical ventilation (MV) (as possible treatment-modifying factors).
During the study period, 55 VLBW
infants were admitted to our NICU, of whom 49 infants were included in the analysis after excluding two infants with chromosome abnormalities, one with congenital anomalies, and three who died during the first week of life.
In this second group of patients, paracetamol showed 100% of failure, suggesting that, after ineffective ibuprofen treatment, paracetamol in VLBW
is not effective in closing PDA, maybe for its late administration (mean 14 days) or for the patients features in this study (lower GA than other trials or variability in the hemodynamic significance criteria among the studies, showed in Table 3), although it became a safe treatment, without renal or hepatic side effects.
Talavera of the department of pediatrics at Ohio State University, Columbus, and her associates assessed the effects of a multipronged intervention on the rate of necrotizing enterocolitis (NEC) among VLBW
infants admitted to the intensive care nurseries of Nationwide Children's Hospital between January 2010 and December 2013.
[A]t points in the distribution where we do not anticipate treatment differences, economically and statistically significant jumps of magnitudes similar to our VLBW
treatment effects could suggest that the discontinuity we observe at 1,500 grams may be due to natural variation in treatment and mortality in our data.
Healthy children reports, "For every 10 mL/kg/day increase in breastmilk ingested: [very low birth weight] VLBW
babies had increased Bayley Mental Development and Psychomotor Development scores, behavior rating scores, and a 6% decrease in rehospitalization" (Cadwell & Turner-Maffei, 2012, p.
Neurobehavioral assessment predicts differential outcome between VLBW
and ELBW preterm infants.