Drugs prescribed for lupus include nonsteroidal anti-inflammatory agents, such as aspirin or ibuprofen; acetaminophen; belimumab (Benlysta), a new monoclonal antibody; antimalarials such as hydroxychloroquine (Plaquenil) and chloroquine (Aralen); corticosteroids such as prednisone or methylprednisolone; immune suppressants such as azathioprine (Imuran, Asasan); methotrexate (Rheumatrex, Trexall
); mycophenolate mofetil (CellCept); cytotoxic drugs such as cyclophosphamide (Cytoxan) and anticoagulants such as heparin (Calciparine, Liquaemin) and warfarin (Coumadin).
will market the product under the Trexall
trademark and will begin a detailing program directly to physicians starting next month.
Common treatments for rheumatoid arthritis include NSAIDs, disease-modifying anti-rheumatic drugs (DMARDS) such as methotrexate (Rheumatrex, Trexall
), the COX-2 inhibitor Celebrex, aspirin and analgesics to reduce pain, swelling and stiffness.
Common DMARDs include: methotrexate (Rheumatrex, Trexall
), sulfasalazine (Azulfidine), hydroxychloroquine (Plaquenil), leflunomide (Arava), cyclosporine (Sandimmune, Neoral), and azathioprine (Imuran, Azasan).
Drug Brand Names Acetaminophen * Tylenol Lithium * Eskalith, Lithobid Amitriptyline * Elavil, others Methotrexate * Rheumatrex, Amoxapine * Asendin Trexall
Carbamazepine * Tegretol, Milnacipran * Savella Carbatrol, others Nortriptyline * Aventyl, Clomipramine * Anafranil Pamelor Desipramine * Norpramin Olanzapine * Zyprexa Duloxetine * Cymbalta Oxcarbazepine * Trileptal Fluoxetine * Prozac Pregabalin * Lyrica Gabapentin * Neurontin, Topiramate * Topamax, Gralise Topiragen Imipramine * Tofranil Venlafaxine * Effexor Lamotngine * Lamktal Ziprasidone * Geodon Disclosure
A few immunosuppressant drugs, including the cancer drugs cyclophosphamide (Cytoxan) and methotrexate (Rheumatrex and Trexall
), have been shown to be effective in treating the inflammatory stage of scleroderma in some people.
** Methotrexate (Trexall
) is a folic-acid inhibitor generally used to treat rheumatoid arthritis and may be prescribed in rare cases for Sjogren's patients with internal organ involvement.