methotrexate

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Synonyms for methotrexate

toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid

References in periodicals archive ?
Drugs prescribed for lupus include nonsteroidal anti-inflammatory agents, such as aspirin or ibuprofen; acetaminophen; belimumab (Benlysta), a new monoclonal antibody; antimalarials such as hydroxychloroquine (Plaquenil) and chloroquine (Aralen); corticosteroids such as prednisone or methylprednisolone; immune suppressants such as azathioprine (Imuran, Asasan); methotrexate (Rheumatrex, Trexall); mycophenolate mofetil (CellCept); cytotoxic drugs such as cyclophosphamide (Cytoxan) and anticoagulants such as heparin (Calciparine, Liquaemin) and warfarin (Coumadin).
will market the product under the Trexall trademark and will begin a detailing program directly to physicians starting next month.
Common treatments for rheumatoid arthritis include NSAIDs, disease-modifying anti-rheumatic drugs (DMARDS) such as methotrexate (Rheumatrex, Trexall), the COX-2 inhibitor Celebrex, aspirin and analgesics to reduce pain, swelling and stiffness.
Common DMARDs include: methotrexate (Rheumatrex, Trexall), sulfasalazine (Azulfidine), hydroxychloroquine (Plaquenil), leflunomide (Arava), cyclosporine (Sandimmune, Neoral), and azathioprine (Imuran, Azasan).
Drug Brand Names Acetaminophen * Tylenol Lithium * Eskalith, Lithobid Amitriptyline * Elavil, others Methotrexate * Rheumatrex, Amoxapine * Asendin Trexall Carbamazepine * Tegretol, Milnacipran * Savella Carbatrol, others Nortriptyline * Aventyl, Clomipramine * Anafranil Pamelor Desipramine * Norpramin Olanzapine * Zyprexa Duloxetine * Cymbalta Oxcarbazepine * Trileptal Fluoxetine * Prozac Pregabalin * Lyrica Gabapentin * Neurontin, Topiramate * Topamax, Gralise Topiragen Imipramine * Tofranil Venlafaxine * Effexor Lamotngine * Lamktal Ziprasidone * Geodon Disclosure
A few immunosuppressant drugs, including the cancer drugs cyclophosphamide (Cytoxan) and methotrexate (Rheumatrex and Trexall), have been shown to be effective in treating the inflammatory stage of scleroderma in some people.
** Methotrexate (Trexall) is a folic-acid inhibitor generally used to treat rheumatoid arthritis and may be prescribed in rare cases for Sjogren's patients with internal organ involvement.