NSAIDs, such as Motrin/Rufen, Ansaid, Naprosyn/Anaprox, Rimadyl, Voltaren, Clinoril, Feldene, and Tolectin
, should be avoided for the arthritic pain of nursing facility patients as much as possible due to their adverse GI effects in chronic usage.
These reactions should have been recognized as anaphylactic almost immediately, because Zomax is almost identical to Tolectin
, a McNeil prescription arthritis drug that accounts for an extraordinary share of anaphylactic reactions among drugs in its class.
The common NSAIDs still requiring a prescription are naproxen (Naprosyn), piroxicam (Feldene), indomethacin (Indocin), tolmetin sodium (Tolectin
), mefenamic acid (Ponstel), diflunisal (Dolobid), and diclofenac sodium (Voltaren).
One randomized, double-blind, crossover trial compared single doses of tolmetin (Tolectin
, 100, 150, 200 mg) and acetaminophen (400 mg) alone and in combination with placebo in the control of experimentally induced pain (thermal and electrical stimulation).
In July the company began marketing tolmetin sodium (the generic version of McNeil Pharmaceutical's Tolectin
) in 600 mg.