Patients with blood pressure >160/100 mm Hg often are started on a thiazide diuretic
with one other medication because a single agent usually does not achieve goal blood pressure.
Patients using only one type of antihypertensive drug before the development of NOF were categorized as single users based on the antihypertensive drug class prescribed, including loop or thiazide diuretics
, alpha-blockers, beta-blockers, CCBs, ACE inhibitors, and ARBs.
Loop and thiazide diuretics
may cause this clinical picture, but the patient was not taking these drugs.
But research suggests that ACE inhibitors and ARBs aren't as effective in African-Americans, so thiazide diuretics
and CCBs typically are used instead as first-line therapy in these patients.
7 Thiazide Diuretics
Potassium-sparing diuretics can prevent potassium depletion, something the loop and thiazide diuretics
do not accomplish.
1) The earlier version recommended thiazide diuretics
as first-line therapy but included multiple indications for initiating therapy with other drug classes.
Older adults are at risk for developing adverse events if they take thiazide diuretics
to treat high blood pressure, according to a study in the June 2014 issue of the Journal of the American Geriatrics Society.
Elderly people are most at risk, either from overzealous salt restriction or sodium-depleting drugs like thiazide diuretics
Washington, June 17 ( ANI ): Researchers at UT Southwestern Medical Center have found that adults over 65 who have recently begun thiazide diuretics
are at a greater risk for developing metabolic-related adverse events.
It may be used alone or given with other classes of antihypertensives, especially thiazide diuretics
Studies that also evaluated the therapeutic conduct in these patients indicated ACEI as the most used anti-hypertensives, followed by thiazide diuretics
and beta blockers (OBRELI NETO et al.
In regards to thiazide diuretics
, the new NICE guidelines state that Chlortalidone (12.
In a new study, when older adults used thiazide diuretics
during the first nine months, the incidence of hyponatremia (low sodium levels), hypokalemia (low potassium levels), or a decline in renal function increased.
The author cites a study which found that potassium supplements can resolve the exacerbation of metabolic syndrome caused by thiazide diuretics