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  • noun

Words related to karyotype

the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes)

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Confirmation of the chromosomal translocation: Spectral karyotyping (SKY) was performed which showed the balanced reciprocal translocation (BRT) involving only chromosomes 18 and 22.
Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays.
Examples of topics covered include the plasma cell labeling index, multicolor spectral karyotyping, detection of chromosome 13 deletions by fluorescent in situ hybridization, identification and of clonotypic IgH VDJ sequences, real-time polymerase chain reaction of immunoglobulin rearrangements for quantitative evaluation of minimal residual disease, determination of telomerase activity and telomere length, clonality detection of the expanded t-cell populations in patients with multiple myeloma, and use of DNA micrrarray data.
A more comprehensive type of FISH is multicolor karyotyping, spectral karyotyping (SKY) or M-FISH, which can identify aberrations in all chromosomes.
Spectral karyotyping (SKY) was a key diagnostic tool in eight papers presented at the recent annual meeting of the American Association for Cancer Research (AACR) in Philadelphia, PA.
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