He, "The roles and regulation of Sertoli cells
in fate determinations of spermatogonial stem cells and spermatogenesis," Seminars in Cell and Developmental Biology, vol.
The Sertoli cell
in varicocele is reported to be more sensitive than germ cells to changes in the testicular microenvironment  and the structure of the TJ between Sertoli cells
is damaged in experimental varicocele in the rat testis [29,30], implying that the Sertoli cell
may be the primary altered intratubular site, leading to secondary spermatogenesis obstruction.
The lining epithelium consists of germinal and Sertoli cells
, which appeared pyramidal in shape and resting on the basement membrane.
Varner, "Role of Sertoli cell
number and function on regulation of spermatogenesis," Animal Reproduction Science, vol.
Moreover, markers of Sertoli cells
(SOX9) and spermatogonial stem cells (PLZF) were not detected (Figure 2(b)), indicating no contamination with these cells in these LCs.
Caption: Figure 5: Image of the tumor demonstrating the merging of the solid component composed of Sertoli cells
with the Sertoli cells
lining the slit-like spaces (H&E, 400x).
In adult rats, Madhu, Sarkar, Biswas, Behera, and Patra (2011) observed reduction in seminiferous tubular areas, secondary spermatocytes and nuclear diameter of Leydig and Sertoli cells
after 45 days of exposure to 1 mg [kg.sup.-1] bw [day.sup.-1] of 3-MCPD.
This study has demonstrated that testicular tyrosine phosphorylated proteins were localized in Leydig cells, Sertoli cells
, spermatogonia, spermatocytes, and spermatids of adult Sprague-Dawley rats.
Kubinski, "Polycyclic aromatic hydrocarbon-induced cytotoxicity in cultured rat Sertoli cells
involves differential apoptotic response," Environmental health perspectives, vol.
Casali et al., "Genomicindependent action of thyroid hormones on NTPDase activities in Sertoli cell
cultures from congenital hypothyroid rats," Life Sciences, vol.
proliferation induced by follicle-stimulating hormone (FSH) independently of luteinizing hormone activity: evidence from genetic models of isolated FSH action.
Next the scientists devised a cocktail of five transcription factors that activate the epithelial cells' embryonic Sertoli cell
Understanding the role of thyroid hormone in Sertoli cell
development: a mechanistic hypothesis.
Possible hypotheses for this relationship include hypogonadotropic hyperestrogenic hypogonadism due to aromatization of steroids in estrogens in peripheral tissue; direct alterations of spermatogenesis and Sertoli cell
function; hip, abdominal, and scrotal fat-tissue accumulation, leading to increased scrotal temperature; and accumulation of toxins and liposoluble endocrine disruptors in fatty tissue.
The histopathology revealed Sertoli cell
only in the testicular tissue.