- There are 146 pipeline programs in active development for SLE
. What proportion of these products are first-in-class?
The researchers found that during this time frame, an estimated 93,820 pregnant women with SLE
and 78,045,054 without SLE
were hospitalized in the United States.
A case of SLE
was defined as meeting either the 1997 update of the 1982 American College of Rheumatology (ACR) revised classification criteria (meeting four or more of the 11 criteria*) (4,5) or an alternative definition (three of the ACR criteria plus a documented diagnosis of SLE
by the patient's board-certified rheumatologist).
Aim of this study was to determine the frequency of pulmonary hypertension in SLE
patients of Pakistani origin using echocardiography which is non-invasive method and do not require specialized training and can be used in routine clinical practice.8 We want to make a comparison of frequency of pulmonary arterial hypertension in SLE
patients in Pakistan with rest of the world as severity of disease varies in different populations.
Studies have reported that lupus nephritis (LN) is the current leading cause of morbidity and mortality in SLE
patients; LN develops in 50 to 75% of Asian SLE
Between 1968 and 2013, there were 50,249 deaths from SLE
and more than 100.8 million deaths from other causes in the United States, the researchers said.
family we studied might represent an inherited SLE
Classification, Demographics, and Health Status of ILE versus SLE
. More than 94% of patients were female (Table 1), greater than 80% were Caucasian, and more than 90% were non-Hispanic, with no significant differences between the ILE and SLE
groups (data not shown).
specific skin manifestations were as follows: malar rash was seen in 83 (71.6%) patients, photosensitivity in 61 (49.12%) patients, oral ulcers in 39 (31.35%), maculopapular rashes in 29 (23.46%), discoid rash in 26 (20.7%), subacute cutaneous lupus erythematosus (SCLE) in 6 (5.18%) patients.
Global Systemic Lupus Erythematous (SLE
) Drugs market is projected to grow due to high prevalence of autoimmune diseases particularly systemic lupus erythematous (SLE
and ANCA associated vasculitis including granulomatosis with polyangitis, he said, are autoimmune diseases which develop due to failure of immune self-tolerance.
* What is the significance of late-phase pipeline products and how will their launch shape the future treatment landscape in SLE
Systemic Lupus Erythematosus (SLE
) is prototypic multi organ autoimmune disorder (Miah et al 2008).
"When our results, including the onset time of mood or anxiety disorders, are considered, these disorders seem to be secondary to the severity of lupus rather than play a primary role in the exacerbation of SLE
," Turkish researchers led by Dr.