amyotrophic lateral sclerosis

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  • noun

Synonyms for amyotrophic lateral sclerosis

thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord

References in periodicals archive ?
The drug was well tolerated; however, it is believed this outcome is most likely because in ALS the disease process is already so severe and rapidly progressing by the time of diagnosis that any further benefit of olesoxime over that of riluzole cannot be detected.
He worries that patients will jump prematurely to conclusions about riluzole's efficacy.
While riluzole tablets are US FDA approved for ALS, they may be difficult to administer in ALS patients, who typically have difficulty in swallowing.
Further studies are needed to investigate modifications of F wave parameters following UMN dysfunction with disease progression and modulations of F wave parameters by relevant treatment such as riluzole.
Riluzole is thought to decrease the release of glutamate into the extracellular space.
Biohaven has been subsequently informed by the manufacturer that they had an exemption from the FDA to supply riluzole to the U.S.
M2 EQUITYBITES-April 17, 2019-Aquestive submits Riluzole Oral Film NDA with US FDA for ALS
Global Banking News-April 17, 2019-Aquestive submits Riluzole Oral Film NDA with US FDA for ALS
M2 PHARMA-April 17, 2019-Aquestive submits Riluzole Oral Film NDA with US FDA for ALS
There's only been one main treatment for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease--a drug called Riluzole.
He wrote: "I don't fit the criteria because you need to be the last 24 months without any drugs and not to have a feeding tube in and on Riluzole tablets.
The patient was considered as having motor neuron disease because of his clinical and EMG findings and loaded family history, and Riluzole 100 mg/d was initiated.
There is no effective cure for ALS; the medications riluzole (approved in 1995) and edaravone (approved in May 2017, the first drug approved specifically for ALS in 22 years), have modest effects.
At this time, the only FDA-approved medication available for the treatment of ALS is riluzole, which has been shown to prolong survival for only about 2 months (1).