Multiple pregnancies, newborns with major congenital malformations or neural tube defect, patients with Rh incompatibility
Association of ABO and Rh incompatibility
with neonatal hyperbilirubinaemia was researched by Apexa S Patel et al.
17,18 It constitutes hemolysis of milder intensity than the hemolytic disease resulting from Rh incompatibility
8% Figure-1: Causes of neonatal hyperbilirubinemia Sepsis 87 Cephalohematoma 35 ABO incompatibility 318 Rh Incompatibility
71 Unknown 245 Note: Table made from pie chart.
the number of patients and their conditions (as some of the studies included Rh incompatibility
In addition to physiologic jaundice, many conditions are associated with hyperbilirubinemia such as sepsis, twin-to-twin transfusion, hemolysis from Rh incompatibility
, and slowed excretion of bilirubin seen with hypothyroidism and cystic fibrosis (Augustine 1999; Berkowitz 2000).
is a blood disorder in which the mother's immune system attacks the baby's blood cells.
Unrecognized hemolysis such as ABO blood type incompatibility or Rh incompatibility
is less of a problem for the blood supply because about 84 percent of Americans are Rh-positive and even someone who is Rh-negative can withstand one accidental infusion of Rh-positive blood without having a severe reaction.
Though she loves her godson whose blindness is caused by a genetic condition, she and her husband decided not to have any more children after a son was born with Rh incompatibility
The Company's business plan calls for commercialization of diverse Tr-DNA testing applications for detecting and/or monitoring infectious diseases, including AIDS and tuberculosis, and for other applications such as the detection of prenatal gender determination, Rh incompatibility
and Down syndrome.
Significant neonatal unconjugated hyperbilirubinemia can be caused by prematurity, ABO and RH incompatibility
, G6PD deficiency, minor blood group incompatibility or idiopathic aetiology, of which ABO incompatibility is most common aetiology followed by the other causes.
ABO incompatibility, Rh incompatibility
, TORCH infections###None###none
Background: Incidence and the complication rate of Rh incompatibility
varies in different parts of the world and the low incidence of Rh negativity often leads to the neglect of rhesus incompatibility in many parts of Asia.
Despite modern obstetrical practices and the availability of Rh immunoglobulin, Rh incompatibility
remains the leading cause of HDN.