Our patient had neither renal structural nor functional abnormalities, indicating that GATA3 haploinsufficiency in this patient did not reach the threshold that can lead to obvious renal dysplasia
We review the clinical features, pathologic features, pathogenesis, differential diagnosis, and treatments for renal dysplasia
9) noted that prenatal visualization of a urinoma indicates a poor prognosis for the affected kidney and should be considered an ultrasonographic sign of renal dysplasia
Pulmonary hypoplasia caused by oligohydramnios is the most common cause of death in the first few hours after birth, while renal dysplasia
, which is a consequence of the high urinary tract pressures, results in irreversible chronic renal failure.
Hawkins CF, Smith OE (1950) Renal dysplasia
in a family with multiple hereditary abnormalities including iliac horns.
Ultrasonographic findings of renal dysplasia
in cocker spaniels: eight cases.
There's one spina bifida, one microcephaly, a couple of renal dysplasias
, a hypospadias.
Reflux should be suspected in children with hydroureter, multicystic renal dysplasia
, ureteral duplication, and ureterocele.
and obstructive uropathy are the predominant causes in the first five years of life.
For example, a child with a pattern of characteristics including vertebral defects, an imperforate anus, tracheoesophageal fistula, radial and/or renal dysplasia
(and perhaps limb defects) can today be diagnosed with VATER association.
Patients were retrospectively divided into three groups based on the degree of defined renal function: group 1, severe renal failure, leading to death (19 cases: 17 terminations of pregnancy with marked oligohydratiitlios with hyperechogenic parenchyma, and 2 neonatal deaths from acute pulmonary hypoplasia and renal failure; renal dysplasia
confirmed postmortem in all 19 cases); group 2, moderate renal failure, serum creatinine (Jaffe method) at 1 year >50 [micro]mol/L (19 cases); and group 3, normal renal function, serum creatinine at 1 year <50 [micro]mol/L (33 cases).
The next day, she was rushed to Children's Hospital of Philadelplaa, where she was diagnosed with several serious kidney disorders--renal agenesis, renal dysplasia
and grade IV bilateral vesicoureteral reflux.
All the three affected members suffered from sensorineural deafness and hypocalcemia; however, renal dysplasia
only appeared in the youngest patient.
On antenatal ultrasound the appearance is that of marked distension and hypertrophy of the bladder, with or without hydronephrosis and hydroureter, and depending on the severity, oligohydramnios and renal dysplasia