The study previously reported its primary endpoint at six weeks, demonstrating non-inferiority of Inflectra compared to Remicade
in the treatment of CD.
is the brand name for the company's version of a biological medicine called infliximab, which is used mainly in the treatment of patients with gastroenterology and rheumatology conditions such as Crohn's disease, ulcerative colitis and rheumatoid arthritis.
In a statement the CMA said: "The CMA has provisionally found that MSD broke competition law by abusing its dominant position through a discount scheme for Remicade
that was likely to restrict competition from 'biosimilar' versions of infliximab that were new to the market.
is J&J's biggest seller, accounting for nearly 10% of the company's revenue.
A spokesman claimed England was "now one of the few countries in the world" that does not use drugs like Humira and Remicade
High uptake of off-label biologies (Rituxan, Lemtrada, Remicade
At the heart of the dispute is the merger of Merck and Schering-Plough, which was cleverly designed to enable Merck to retain the Remicade
It is an antibody like Remicade
, but it is derived completely from human proteins, and it is administered by subcutaneous injection every two weeks.
Centocor exclusively markets REMICADE
and upon approval will market golimumab in the United States.
As with other immune modifiers, there is a warning about the increased risk for serious infections associated with Remicade
treatment, and the potential for an increased risk of malignancies.
When used in combination with Methotrexate, Remicade
achieves the maximum clinical effect by stopping joint destruction.
Enbrel, Humira (adalimumab), Kineret (anakinra), Remicade
(infliximab), methotrexate, azathioprine, and Celebrex are among them.
Special Considerations: The risk of serious infections is increased with Remicade
announced today that REMICADE
[R] (infliximab) has been approved by the FDA for the treatment of ulcerative colitis (UC), making REMICADE
the first and only biologic approved for UC, a chronic inflammatory bowel disease (IBD).