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Words related to thrombin

an enzyme that acts on fibrinogen in blood causing it to clot

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Prothrombin G20210A mutation, but not factor V Leiden, is a risk factor in patients with persistent foramen ovale and otherwise unexplained cerebral ischemia.
4,5] Several studies demonstrated that the prothrombin gene mutation had no effect on arterial thrombosis, [6-9] although some authors suggested that the prothrombin G20210A mutation was weakly associated with some arterial thrombosis [4,10,11] Mueller et al.
Thus, incidences of an inhibitor deficiency, prothrombin G20210A mutation or combined thrombophilia were almost negligible in the older women.
4-6) Women with familial coagulation disorders, including factor V Leiden mutation, prothrombin G20210A mutation, deficiencies of anticoagulant proteins (antithrombin, protein C, protein S), and elevations in procoagulant factors (factor VIII, factor IX, factor XI), are 2 to 8 times more likely to experience a VTE event than are unaffected individuals.
16) Tests ordered should include Factor V Leiden (APC resistance), protein S deficiency, protein C deficiency, antithrombin as say, Prothrombin G20210A mutation, factor VIII activity, homocysteine level, and Lupus anticoagulant.
The number of patients with the prothrombin G20210A mutation was 63 (7%).
It would then appear that 1 of our 2 patients who is homozygous for the FVL mutation and heterozygous for the prothrombin G20210A mutation has a substantially greater risk compared with a doubly heterozygous patient, possibly explaining in part the fact that this patient had 10 episodes of thrombosis by the time of analysis.
Factor V Leiden and prothrombin G20210A mutation allele frequencies in Europeans are been reported to be 1.
Matched case-control study on factor V Leiden and the prothrombin G20210A mutation in patients with ischemic stroke/TIA up to the age of 60 years.
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