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Related to Prothrombin g20210a mutation: Prothrombin 20210a mutation
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  • noun

Words related to thrombin

an enzyme that acts on fibrinogen in blood causing it to clot

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A team of researchers from two French institutions, the University Hospital in Nimes and the University of Montpellier 1, studied 160 pregnant women with genetic risk factors for thrombophilia (heterozygous factor V Leiden mutation, prothrombin G20210A mutation, or protein S deficiency) who had experienced one unexplained stillbirth at 10 weeks gestation or later prior to the study.
It would then appear that 1 of our 2 patients who is homozygous for the FVL mutation and heterozygous for the prothrombin G20210A mutation has a substantially greater risk compared with a doubly heterozygous patient, possibly explaining in part the fact that this patient had 10 episodes of thrombosis by the time of analysis.
Factor V Leiden and prothrombin G20210A mutation allele frequencies in Europeans are been reported to be 1.
Matched case-control study on factor V Leiden and the prothrombin G20210A mutation in patients with ischemic stroke/TIA up to the age of 60 years.
The odds ratios (ORs) for VTE associated with values below the 10th percentiles were derived from 2 x 2 tables (univariate OR) or from a logistic regression model that included VTE as the dependent variable and age, sex, hormone treatment, the FV Arg506Gln mutation, and the prothrombin G20210A mutation as independent covariables.
Association of the prothrombin G20210A mutation with factor V Leiden in a Midwestern American population.
In this report, we describe the novel application of the Factor II Invader[R] assay for the genotyping of patient specimens for the prothrombin G20210A mutation.
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