This approach may bypass the challenges presented by stem cell therapies by temporarily reactivating progenitor cells
already located at the tissue target site and pre-programmed to make specific cell types.
Nishio, "Endothelial progenitor cell
senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension," Journal of Hypertension, vol.
come from stem cells and serve many functions in repairing and maintaining tissues throughout our bodies.
The PI3K/Akt/mTOR pathway mediates retinal progenitor cell
survival under hypoxic and superoxide stress.
Consequently, as the endothelium and inflammatory cells play a crucial role in the development of collaterals after a sudden or slowly progressing stenosis of coronary arteries, endothelial progenitor cells
and soluble adhesion molecules determine the formation and the quality of the collaterals.
The business of Progenitor Cell
Therapy is expected to add to NeoStem's adult stem cell business.
In an attempt to identify the possible source of cells which maintain the tissue turnover, we used CD 34, a well established marker of peripheral blood stem cell in healthy human gingiva to determine the origin of progenitor cells
in healthy gingiva.
Spheres are made up primarily of pluripotential progenitor cells
that are capable of differentiating into cell types from the three germ layers.
Frequency Therapeutics develops small molecule drugs to stimulate progenitor cells
in the body to reverse biological deficits and restore healthy tissue.
In a paper that appeared online March 15 in the journal Science, the researchers describe a model for planarian (flatworm) eye regeneration that is governed by three principles acting in concert, which inform how progenitor cells
behave in regeneration.
The endothelial progenitor cell
(EPC) has been reported as a promising cell source for promoting neovascularization [9, 10].
Microscopy of progenitor cell
adhesion and survival
The findings provide new insights into the role and importance of exosomes and their targeted gene transcripts, and may help point the way to new drugs or therapies for not just skin diseases, but other disorders in which stem and progenitor cell
populations are affected.
Oxidative stress impairs endothelial progenitor cell
Stanford University (Palo Alto, CA) has patented a substantially enriched mammalian hematopoietic cell subpopulation, which is characterized by progenitor cell
activity for lymphoid lineages, but lacking the potential to differentiate into myeloid and erythroid lineages.