3) The combination of Katz's and Weber's knowledge led to the development of phentolamine mesylate to counter the effects of the vasoconstrictor epinephrine.
Therefore, phentolamine mesylate has not been tested for efficacy following use of local anesthetic without added vasoconstrictors.
The delivery method of phentolamine mesylate is similar to that of local anesthesia; it comes in a cartridge like that of regular local anesthetics.
The FDA recommended that the Company conduct another two year rodent study due to concerns about the previously reported brown fat proliferations observed in the course of the earlier two year rat study in which phentolamine mesylate
, the active ingredient in VASOMAX(R), was administered on a daily basis.
Vasomax(R) is the Company's first product, an oral treatment for Male Erectile Dysfunction (MED) that is a proprietary form of phentolamine mesylate delivered in a rapidly disintegrating tablet.
Vasofem is a vaginal dosage form of phentolamine mesylate, the active ingredient in Vasomax(R).
Vasomax(R) is Zonagen's rapidly disintegrating oral formulation of phentolamine mesylate
for the treatment of male erectile dysfunction that is currently under regulatory review by the U.
for Vasomax(R), Zonagen's rapidly disintegrating oral formulation of phentolamine mesylate
for male erectile dysfunction.
The study, conducted by the Chicago Center for Clinical Research, is designed to evaluate the safety and pharmacokinetics of phentolamine mesylate
in sixty healthy patients.
Vasomax(R), Zonagen's rapidly-disintegrating oral formulation of phentolamine mesylate
, was licensed worldwide to Schering-Plough Corporation on November 17, 1997 for the treatment of male erectile dysfunction.
Vasomax(TM), Zonagen's rapidly-disintegrating oral formulation of phentolamine mesylate
, has been tested in over 300 men in Mexico and more than 3,000 men in the U.