Parkinson's disease

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Related to Parkinsonian: Parkinsonian gait, parkinsonian syndrome
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Synonyms for Parkinson's disease

a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination

References in periodicals archive ?
"The present study shows that patients with incident parkinsonism have reduced survival but that the survival is highly dependent on the type and characteristics of the parkinsonian disorder."
Multiple system atrophy (MSA) is an adult onset, progressive, idiopathic neurodegenerative disease that involves, to varying degree, the basal ganglia, olivopontocerebellar complex and autonomic system.1-3 It has three clinical subtypes: MSA-C when cerebellar signs are predominant, MSA-P when parkinsonian features are predominant and MSA-A when the patient presents with autonomic signs and symptoms.3 The presence of hot cross bun sign on T2WI is a powerful tool for diagnosis of MSA-C in appropriate clinical setting.
Wszolek, "Atypical parkinsonian syndromes: a general neurologist's perspective," European Journal of Neurology, vol.
To date, all patients carrying concomitantly 22q11.2 deletions and parkinsonian features were negative for a family history of PD and any known pathogenic PD-related mutations.
Parkinsonian features can occur in hydrocephalus due to involvement of terminal dopaminergic neurons bordering the lateral ventricles [8] or due to mechanical distortion and consequent vascular insufficiency in the nigrostriatal system.
Reduction in dopamine interferes with the brain's ability to produce smooth physical movement, resulting in dystonia, tremor, and/or parkinsonian symptoms.
An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.
Several factors can help you and your doctor determine if your shakiness is from ET or if it's a parkinsonian tremor.
There are two clinical subtypes depending on the predominant motor presentation: a Parkinsonian variant reflecting underlying nigrostriatal degeneration (MSA-P) and a cerebellar variant associated with cerebellar ataxia (MSA-C) [1].
MRI guidance improves accuracy of stereotaxic targeting for cell transplantation in Parkinsonian monkeys.
Early dopaminergic drug-induced hallucinations in parkinsonian patients.
A correlation exists between diabetes severity and parkinsonism, or parkinsonian tremors, according to research at the University of Pennsylvania, Philadelphia.