David

Osteosarcoma amplified 9 (OS-9), an endoplasmic reticulum (ER) lectin, is a protein coding gene located on 12q13 chromosome of humans.

Of all the meprin substrates identified to date, OS-9 provides the most direct link to the hypoxia response and provides new insights on how meprins modulate tubular injury in IR.

Shaltiel, "A selective interaction between OS-9 and the carboxyl-terminal tail of meprin [beta]," The Journal of Biological Chemistry, vol.

Oh et al., "OS-9 interacts with hypoxia-inducible factor 1[alpha] and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1[alpha]," Molecular Cell, vol.

Meltzer, "Complete sequence analysis of a gene (OS-9) ubiquitously expressed in human tissues and amplified in sarcomas," Molecular Carcinogenesis, vol.