Nydrazid

The 3HP group was given once weekly, directly observed treatment with rifapentine (brand name Priftin; 900 mg) plus isoniazid (brand name Nydrazid, also known as isonicotinic acid hydrazide or INH; 15-25 mg/kg) for 3 months.

TABLE 6 Agents with reported potential drug interactions (20-23, 25-26, 32, 33, 45) Drug Possible interactions Histamine 2 Fluoxetine (Prozac), chemotherapy drugs, cyclosporine receptor (Sandimmune, Neoral, Restasis), warfarin (Coumadin, antagonists Jantoven), carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), isoniazid (Nydrazid), ciprofloxacin (Cipro, Proquin XR), ketoconazole (Nizoral, Xolegel), valproic acid (Depakene, Depakote, Stavzor), theophylline (Theo-Dur, Theolair, Slo-phyllin), and midazolam Proton pump Warfarin (Coumadin Jantoven), atazanavir (Rayataz), inhibitors ketoconazole (Nizoral, Xolegel), iron salts, digoxin (Lanoxin, Digitek), cyclosporine (Sandimmune, Neoral, Restasis), and tacrolimus (Protopic, Prograf), clopidogrel (Plavix)

* Drug-induced lupus is caused by certain medications, the most common being: procainamide (Pronesyl), used for heart rhythm abnormalities; hydralazine (HydraZide), used for high blood pressure; and isoniazid (Nydrazid), used for tuberculosis.

Last year the company reintroduced Nydrazid for treating tuberculosis.