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Related to Nucleoside reverse transcriptase inhibitors: Protease inhibitors
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  • noun

Synonyms for NRTI

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Rio DE JANEIRO -- The novel nucleoside reverse transcriptase inhibitor Reverset is poised to become the newest member of the oldest class of antiretroviral agents, with researchers reporting its promise for HIV-infected patients for whom current antiretroviral regimens have failed and who have NRTI resistance.
67 for high ALT), and the same was true among those on multiple nucleoside reverse transcriptase inhibitors (OR of 1.
Newer drugs are selecting for different types of resistance, especially in nucleoside reverse transcriptase inhibitors (NRTIs), so that there may not be large numbers of thymidine analog mutations (TAMs) developing in patients who have started therapy in recent years.
Also, among patients on multiple nucleoside reverse transcriptase inhibitors, platelet counts of less than 99,000/m[m.
In addition, ZDV and 3TC caused fewer adverse effects than combinations with different nucleoside reverse transcriptase inhibitors, didanosine (ddI) and stavudine (d4T).
Surprisingly, support for this notion has come from testing the effect of removing single drugs from a failing regimen--in particular, nucleoside reverse transcriptase inhibitors (NRTIs).
Each dose of Trizivir is a fixed-dose combination of Ziagen (abacavir/ABC), Retrovir (zidovudine/AZT), and Epivir (lamivudine/3TC), three nucleoside reverse transcriptase inhibitors (NRTIs) already approved by FDA.
However, these 25 patients, all of whom were naive to non-nucleoside reverse transcriptase inhibitors (NNRTIs), were given efavirenz (Sustiva), a potent NNRTI, in addition to Kaletra and nucleoside reverse transcriptase inhibitors (NRTIs).
The French have reported 8 cases of mitochondrial toxicity in uninfected infants with neonatal exposure to nucleoside reverse transcriptase inhibitors (NRTIs) who developed neurological and developmental abnormalities leading to 2 deaths.
The 3 components of Trizivir, all nucleoside reverse transcriptase inhibitors, have been previously approved for use in the United States.
Usually one PI is combined with 2 nucleoside reverse transcriptase inhibitors (NRTIs), the first class of approved antiretroviral drugs.
If you are having trouble adhering to a standard 3-drug regimen, talk to your doctor about taking 2 nucleoside reverse transcriptase inhibitors (NRTIs) only.
Soon the benefit of combining therapies began to become clearer (the combination trend had actually begun earlier with nucleoside reverse transcriptase inhibitors, NRTIs), and the treatment paradigm of 2 NRTIs and a PI became the unique model by which other therapies were measured.
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