In human medicine, BG tumors are thought to arise from the mucin-secreting columnar glandular epithelial cells (FINAN & BARRE, 2003; WILKINSON & TEIXEIRA, 2003), or from the squamous epithelium of the vestibular orifice (FINAN & BARRE, 2003; HELLER & BEAN, 2014); in this case the neoplastic growth
probably originated from proliferated glandular epithelial cells.
(1) We all know that neoplastic growth
depends not only on cell death (Apoptosis), but also on cell proliferation which is an important feature of dysplasia and carcinoma.
Interestingly, MCP-1 can be released also by macrophages located in the region of neoplastic growth
The hydroalcoholic extract of the medicinal plant Bursera fagaroides presents immunomodulatory activity and diminishes neoplastic growth
in the BALB/ c murine L5178Y lymphoma model.
(9,10) Some studies have suggested that the lack of thyroid hormones delays neoplastic growth
and improves chemotherapeutic treatment prognosis.
Fecal occult blood is an indirect marker for neoplasia, whereas mutations in oncogenes and tumor suppressor genes are directly associated with neoplastic growth
A diagnosis of leiomyoma is mainly based on gross and histological appearance of neoplastic growth
.The present diagnosis was confirmed by appearance of a mixture of plain muscle and fibrous tissue arranged in all directions and planes.
Differential diagnosis include benign lesion such as simple cyst and pseudocyst, (4) and necrotic neoplastic growth
such as liposarcoma, leiomyosarcoma, fibrosarcoma, teratoma, (2) or metastatic lymphadenopathy and in Indian context multi loculated ascitis due to high prevelance of tubercular abdomen.
Histologically, the right testicular parenchyma was diffusely affected and replaced by neoplastic growth
, consisting of sheets of large round to polyhedral cells with conspicuous vesicular nuclei having distinctly granular chromatin and prominent nucleoli.
To rule out any chances of neoplastic growth
or abscesses fine needle aspiration was performed.
On histologic sections, they usually show effacement of normal tissue architecture with a nodular (seen in FL; Figure 1, A) or diffuse (seen in CLL/SLL) pattern of neoplastic growth
. The growth pattern is often highlighted by immunohistochemical analysis, particularly B-cell antigen markers (Figure 1, A, inset).
The clinical laboratory findings described in this study were not suggestive of neoplastic processes, but only reflected the consequences of the neoplastic growth
in one dog that had severe loss of blood; these results suggest that routine clinical laboratory evaluations might not be of any diagnostic significance in canine chemodectoma.