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an oral antagonist against the action of opiates

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This index increased in animals treated with different protocols using naltrexone hydrochloride, however, only animals that received the antagonist during prenatal period showed a statistically significant increase, approximately 30%, compared to control animals (Table 4).
NYSE: PFE) announced top-line results today from a Phase 3 open-label long-term safety study of investigational agent ALO-02 (oxycodone hydrochloride and naltrexone hydrochloride extended-release capsules) in patients with moderate-to-severe chronic, non-cancer pain.
EMBEDA([R]) contains pellets of an extended-release oral formulation of morphine sulfate, an opioid receptor agonist, surrounding an inner core of naltrexone hydrochloride, an opioid receptor antagonist indicated for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time.
PXT-3003 is an oral fixed-low dose combination of (RS)-baclofen, naltrexone hydrochloride and D-sorbitol which has been developed via the Pharnext Pleotherapy R&D platform.
However, Barr also debuted several other generic products during its recently completed fiscal year, including the hormonal replacement therapies estradiol and estropipate; triamterene and hydrochlorothiazide capsules for the treatment of hypertension or edema, and naltrexone hydrochloride tablets used in the treatment of alcohol dependence and to block the effects of opioids.
Effective immediately, the company will submit a 505(b)(2) New Drug Application for its lead opioid abuse-deterrent candidate ELI-200, immediate-release Oxycodone Hydrochloride 5mg, 10mg, 15 mg, 20 mg and 30mg capsules with sequestered Naltrexone Hydrochloride, for the treatment of moderate to severe pain with the US FDA.
In addition, the company revealed EMBEDA reportedly contains pellets of morphine sulfate, an opioid agonist, with a sequestered core of naltrexone hydrochloride, an opioid receptor antagonist.
Elite Pharmaceuticals Inc (OTC BB:ELTP), a provider of oral sustained and controlled release products, reported on Wednesday the receipt of approval for its supplemental application for the manufacturing and packaging of naltrexone hydrochloride 50 mg tablets.
ELI-216 is a combination of a narcotic agonist, oxycodone hydrochloride, and an antagonist, naltrexone hydrochloride, formulated to deter abuse of the drug.