The most frequently observed adverse effects include myelosuppression
, fatigue, and mucositis, and cellulitis of lower limbs has rarely been reported as an adverse event induced by pemetrexed.
if severe can lead to life threatening infections and hemorrhage.
Moderate or severe myelosuppression
is the major complication after chemotherapy plus HAART.
It also reviews key players involved in the therapeutic development for Chemotherapy Induced Myelosuppression
and special features on late-stage and discontinued projects.
Side-effects include skin rash, myelosuppression
, neurotoxicity, fatigue, nausea, vomiting, diarrhoea and myalgia and arthralgia.
Induction of Myelosuppression
in Mice: Myelosuppression
was induced in experimental mice by a single intraperitoneal injection of carboplatin (Pharmaplatin Inj.
The three major drugs in this area all have side effect issues: Zyvox has been reported to cause myelosuppression
, hematological adverse events, and optic neuropathy, whereas Invanz and Zosyn are associated with hypersensitivity reactions, and Invanz has the potential to cause seizures.
Unlike traditional cytotoxic agents, Erlotinib and Gefitinib do not typically cause myelosuppression
, neuropathy, alopecia, or severe nausea.
While the most frequently reported adverse reactions associated with TREAKISYM include myelosuppression
, nausea, vomiting, infection, vasculitis and angialgia, the agent maintains a manageable and highly tolerable safety profile.
They have greater potency, can be taken orally once daily, and have solved some of the problems associated with linezolid - no hypertension, better gastrointestinal absorption, and less risk of myelosuppression
: Patients may experience grade 3-4 myelosuppression
with some oral agents.
They have greater potency, can be taken orally once daily, and have solved some of the problems associated with linezolid--no hypertension, better gastrointestinal absorption, and less risk of myelosuppression
9 Its major drawback is the risk of myelosuppression
(decrease in the production of blood cells by the bone marrow) was the most common adverse reaction associated with satraplatin therapy, with 98.
Failure to metabolize thiopurines can result in myelosuppression
and hepatotoxicity, which can lead to death.