For example, acethylcholine through its muscarinic receptor
increases the frequency of spontaneous inhibitory postsynaptic current (IPSC's) in GABAergic neurons.
subtypes and management of the overactive bladder.
Lemay, "Mental dysfunction and the blockade of muscarinic receptors
in the brains of the normal elderly," Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol.
The activation of SERCA and muscarinic receptors
mediates these effects, and NO is not involved in the cardiovascular effects of DECC.
M1, M3 and M5 muscarinic receptors
stimulate mitogen-activated protein kinase.
are present in various areas of the brain, which are innervated by cholinergic neurons, both on neurons and glias, and both on postsynaptic and presynaptic membranes.
Dry mouth, constipation, and blurred vision are caused by the drugs binding to muscarinic receptors
in the salivary glands, gastrointestinal tract, and ciliary muscle of the eyes (Abrams & Andersson, 2007).
To assess whether nitric oxide, cGMP, phosphodiesterase-5, [K.sup.+.sub.ATP] channels, prostanoid, betareceptor, L-type calcium channels, or muscarinic receptors
are related to the relaxant mechanisms induced by ayanin, this flavonoid was added to rings contracted with PE treated 30 min.
The effects observed for the selective antagonists suggested that chagasic rats have alterations on the muscarinic receptors
distributions in the central vagal nuclei, cardiac intrinsic ganglion or cardiac muscle cells.
Normal bladder contraction results from cholinergic innervation by the parasympathetic nervous system and activation of muscarinic receptors
on the detrusor muscle.
At the level of the endplate, acetylcholine binds to muscarinic receptors
. Anticholinergic agents such as oxybutynin, oxytrol, tolterodine, and solifenacin succinate are often used to inhibit detrusor muscle contraction.
The scientists focused on muscarinic receptors
, which regulate the speed of the heart, contraction of the pupil, and other bodily functions.
Symptoms similar to CAS may be seen after high-dose fentanyl anaesthesia through binding to muscarinic receptors
, but we used only a low dose of fentanyl.
Anticholinergic medications act on muscarinic receptors
. (There are five known structural subtypes of muscarinic receptors
, designated [m.sub.1], through [m.sub.5].
Food and Drug Administration has approved a muscarinic receptor
antagonist for treating overactive bladder that is more selective to the muscarinic receptors
in the bladder than some older drugs in this class.