The inherited gene that is responsible for FMF is the Mediterranean Fever
Ancient missense mutations in a new member of the RoRetgene family are likely to cause familial Mediterranean fever
We are very excited to introduce the first automated molecular assay for Familial Mediterranean Fever
," said Fareed Kureshy, President and CEO of AutoGenomics.
Neutrophil-lymphocyte ratio in patients with familial Mediterranean fever
Severe outcome of juvenile idiopathic arthritis (JIA) associated with familial Mediterranean fever
25 September 2014 - Swiss medical bioinformatics specialist Sophia Genetics SA said Wednesday that it had obtained a CE-IVD mark for genetic testing of Familial Mediterranean Fever
Although Mutual's formulation of colchicine gained approval as an orphan drug for Familial Mediterranean Fever
, the company conducted no new clinical trials with patients with FME The package insert states the evidence for efficacy in FMF and for gout prophylaxis "is derived from the published literature"--studies that ironically used the same unapproved colchicine that Mutual/URL seeks to force off the market.
Familial Mediterranean fever
(FMF) is an autoinflammatory disease mainly affecting populations surrounding the Mediterranean basin, with a genetic prevalence reaching 1-6% (1).
Other uncommon and miscellaneous causes of fever of unknown origin include familial Mediterranean fever
, which occurs in people native to the Mediterranean area, and presents with recurrent episodes of fever, pelitonitis, or pleuritis; Whipple's disease, which presents with malabsorption and low-grade fever; Weber-Christian disease, which is a nonsuppurative panniculitis; and cosinophilic fasciitis, which presents with bronchial asthma, eosinophilia, and inflammation of the fascia, presenting as areas of induration, particularly in the upper extremities.
Ricke discovered the causative gene for the human disease Familial Mediterranean Fever
in collaboration with the FMF Consortium (Cell 90: 797-807 (1997)).
Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS); Hyperimmunoglobulin D Syndrome (HIDS)/Mevalonate Kinase Deficiency (MKD); and Familial Mediterranean Fever
3) In this article, we report a case of periodic fever syndrome clinically compatible with TRAPS presenting in a young infant with combination of C30Y mutation in the TNFRSF1A gene and a heterozygous, milder familial Mediterranean fever
associated variant in the Mediterranean fever
(MEFV) gene (K695R).
Methods: The study was conducted from March to May 2013 at Mustafa Kemal University Turkey and comprised children with Familial Mediterranean Fever
and healthy controls.
M2 PHARMA-June 5, 2014-Multiplicom to introduce DNA mutation detection kits for Cystic Fibrosis, Familial Mediterranean Fever