nitrogen mustard

(redirected from Mechlorethamine)
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  • noun

Words related to nitrogen mustard

a toxic compound resembling mustard gas in structure

References in periodicals archive ?
The in vivo genetic activity profile of the monofunctional nitrogen mustard 2-chloroethylamine differs drastically from its bifunctional counterpart mechlorethamine.
Sodium thiosulfate is used in the treatment of mechlorethamine (nitrogen mustard) burns (Dorr, 1990; Oncology Nursing Society, 1992).
Mechlorethamine Pronunciation: Me-klor-ETH-a-meen Commonly referred to as: Nitrogen Mustard Brand names: A commonly used brand name is Mustargen[R].
Valchlor gel has been formulated as a once-daily, topical application that dries on the skin, and it is the only FDA-approved formulation of mechlorethamine.
Chemotherapeutic regimens currently recommended for Hodgkin lymphoma are: ABVD- doxorubicin (Adriamycin), bleomycin, vinblastine, dacarbazine; Stanford V mechlorethamine, vincristine, prednisone, doxorubicin, bleomycin, vinblastine, etoposide; and COPP- cyclophosphamide, Oncovin, procarbazine, prednisone.
If it gets clearance, VALCHLOR would be the first and only FDA-approved topical formulation of mechlorethamine for the treatment of early-stage mycosis fungoides-type cutaneous T-cell lymphoma, the pair notes.
Richard Schilsky, on the 60th anniversary of the approval of mechlorethamine, p.
Sodium thiosulfate is the only antidote currently recommended by ONS for extravasation of mechlorethamine or concentrated cisplatin.
MOPP - mechlorethamine + oncovin (vincristine) + procarbazine + prednisone
The drug is known in the USA as mechlorethamine gel and is currently undergoing review by the US drug regulator for early stage (stages I-IIA) mycosis fungoides, a type of CTCL.
Until 1946, government secrecy restrictions prevented publication of small case series, but the experiments continued, and on March 15, 1949, mechlorethamine (Mustargen) became the first chemical agent to receive Food and Drug Administration approval for the treatment of cancer, transforming an agent of death into one that held the promise of extended life and launching a revolution.
M2 PHARMA-October 4, 2011-FDA accepts for filing Yaupon's mechlorethamine gel NDA(C)2011 M2 COMMUNICATIONS