clinical depression

(redirected from Major Depressive Disorder)
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Related to Major Depressive Disorder: major depressive episode, generalized anxiety disorder
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Synonyms for clinical depression

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"We did not find evidence that the addition of fluoxetine (rather than placebo) to CBT further reduced depressive symptoms in young people with moderate-to-severe major depressive disorder," the authors write.
Individuals with major depressive disorder were randomized to the high-dose group, three 90-minute classes a week along with home practice, or the low-dose group, two 90-minute classes a week, plus home practice.
Stein and his team also used the data to determine risk factors for PTSD and major depressive disorder after mTBI.
He presented a cohort study in which he and his coinvestigators utilized comprehensive Swedish national registries to identify 127,087 adults on antidepressant medication for major depressive disorder during 2006-2014.
SSRI-induced treatment-emergent sexual dysfunction (TESD) was assessed directly, with escitalopram as a comparator, in stable patients with MDD in the NCT01364649 trial (Vortioxetine 10 and 20 mg for Treatment of Major Depressive Disorder With Sexual Dysfunction).
The patent has claims to protocols for using NSI-189 and related compounds for treatment of major depressive disorder.
One of the findings from the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) field trials was frustratng due to the very poor inter-rater reliability of clinicians when diagnosing major depressive disorder (MDD).
Because systemic and neural inflammation play important roles in the development of major depressive disorder (Anisman and Hayley 2012), [PM.sub.2.5] exposure--particularly long-term exposure--may increase the risk of major depressive disorder.
An article reported in Translational Psychiatry adds more evidence to the association between higher omega-3 fatty acid intake and a lower risk of major depressive disorder (MDD).
Objective: To determine mean total cholesterol, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) levels in patients suffering major depressive disorder and in healthy controls.
The meta-analysis of 11 randomized trials compared treatment with CBT versus second-generation antidepressants--fluoxetine (Prozac[R]), paroxetine (Paxil[R]) and sertraline (Zoloft[R]) are examples--in a total of 1,511 patients with major depressive disorder. The researchers reported no significant differences between use of the medications and CBT in terms of the participants' response to treatment, remission rates and adverse effects.
"It does have the same symptoms and severity as major depressive disorder and, in fact, the technical name for SAD is 'major depressive disorder, with seasonal pattern.' It's just what we call depression that occurs in the winter and goes away in spring."
[USPRwire, Wed Dec 23 2015] Global Markets Direct's, 'Major Depressive Disorder - Pipeline Review, H2 2015', provides an overview of the Major Depressive Disorder's therapeutic pipeline.
It is frequently seen as a comorbidity with major depressive disorder anxiety generalized anxiety disorder, panic disorder and personality disorder (2).
Coding errors were found in 11 of 30 individual cases that kept veterans from being flagged as having a major depressive disorder. And while a vast majority--94 percent--of those who were actually diagnosed with major depressive disorder were prescribed at least one antidepressant, almost none were treated in accordance with the VA's clinical guidelines or given instruction on how to properly administer their drugs.
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