These actions by the Red Cross have ensured that MDR-TB
medicines are properly used, and have resulted in a 90% treatment completion rate in people who have been under Red Cross supervision.
Assuming proper adherence to national DR-TB management guidelines, the current per patient cost of XDR-TB is ZAR303 508 (USD26 392), four times greater than that of MDR-TB
at ZAR77 878 (USD6 772), and 103 times greater than drug-sensitive TB at ZAR2 955 (USD257).
In the absence of a randomised clinical trial, observational studies strongly indicate that appropriate MDR-TB
chemoprophylaxis should be considered when TB disease has been excluded, there is significant exposure to a close drug-resistant TB contact and the risk of disease progression is high.
11) Another NAAT, the MTBDRplus assay (Hain Lifesciences, Nehren, Germany), offers similar advantages as Xpert[R] MTB/RIF for MDR-TB
is a form of TB that does not respond to at least two preliminary drugs to treat the disease.
Drug resistance and especially MDR-TB
are increasing globally, mainly on account of drugs being improperly prescribed (e.
46,000 in 2010 - this is just 16 per cent of the estimated number of MDR-TB
The Lilly MDR-TB
Partnership, an initiative of Eli Lilly and Company, was established in 2003 to confront multi-drug resistant tuberculosis (MDR-TB
Many countries have made progress, but despite the recent scale up in efforts, the world needs to do much more to get care to all MDR-TB
patients who need it," said Margaret Chan, Director-General of the UN World Health Organization (WHO).
Controlled clinical trials in diverse settings enrolling patients suspected of TB or MDR-TB
detected that among MTB-culture-positive patients a single MTB/RIF test identified 98.
The prevalence of MDR-TB
is increasing throughout the world both among new tuberculosis cases as well as among previously-treated ones (1).
Initially, the MDR-TB
treatment program in Tomsk was created to curb one of the world's most persistent epidemics of drug-resistant tuberculosis.
25" companion document to the WHO's Guidelines for Programmatic Management of Drug Resistant Tuberculosis will help health workers diagnose MDR-TB
, initiate second-line anti-TB drugs, and monitor treatment.
Caption: A man co-infected with HIV and MDR-TB
receives attention from an occupational therapist at home.
Every year, some 2m people die from TB and around 450,000 people will develop MDR-TB
, which is more difficult and expensive to treat.