[6,7] The first-line LPA has a laboratory turnaround time of ~5 hours, allowing for both rapid diagnosis of MDR-TB
and early initiation of treatment.
'In the past, MDR-TB
was a diagnosis that left patients with few options.
was found positive in 40 (42.1%) cases out of 95 enrolled Cat-II patients of tuberculosis.
It is important to perform randomized, controlled clinical trials on how best to provide preventive care for people who come in close contact with individuals with MDR-TB
, since this is a major gap in global public health policy, said Anthony S.
What is MDR-TB
? When patients are given drugs or antibiotics that are incomplete, or are of poor quality, or when patients stop treatment before they are cured, this becomes an opportunity for bacteria to mutate and become drug-resistant.
This must also be coupled with investment to fulfill all prisoners' right to health, meaning they have access to life-saving TB screening, diagnostics and treatment services.Incarcerating TB patients who have challenges adhering to their treatment, while intended as a means to stop MDR-TB
in its tracks, must be firmly rejected on human rights grounds and recognised as an ineffective and inhumane way to address the problem.
If everything went according to plan, he said, the intention was to start administering the new treatment for MDR-TB
patients by October.
Considering, the prevalence of MDR-TB
(1-3% in new cases and around 12% in re-treatment cases) in India, the sample size calculated is 8 for new cases and 41 in re-treatment cases, using following formula:
Chi-square test was applied for finding significant association between the categories of variables- that is to find association of MDR-TB
and Type 2 DM.
Studies that estimated rate of MDRTB and/or identified factors associated with MDR-TB
were systematically reviewed.
Material and Methods: A cross sectional study in which four hundred and eighty sputum samples from MDR-TB
patients' attendants were processed for the detection of M.TB through Ziehl-Neelsen staining, Lowenstein-Jensen, BACTEC MGIT-960 culture and line probe assay.
This grant in particular will help Akonni accelerate the commercialisation of its proprietary TruArray MDR-TB
test on its TruDx3000 sample-to-answer diagnostic platform.
He is also the former President of International Union Against Tuberculosis and Lung Disease (The Union) and among key researchers conducting the STREAM study comparing effectiveness of shortened treatment regimen for multidrug-resistant TB (MDR-TB
is defined as Mycobacterium tuberculosis that is resistant to both isoniazid (INH) and rifampicin (RIF), regardless of other susceptibilities.
Although TB is typically a treatable disease, cases of multidrug resistant TB (MDR-TB
) that are resistant to the first-line drugs rifampin and isoniazid have emerged in recent years, presumably due to inadequate treatment or subtherapeutic drug concentrations.