The reason for this is the fact that the drop of lymphocyte count
was more pronounced in the appendicitis group in which the increase in neutrophil count was the highest.
In conclusion, our results revealed that isotretinoin therapy led to a decrease in WBC count, absolute lymphocyte count
, and MPV in patients with acne.
Mean neutrophil counts of the study groups were not statistically different (p=0.58), however, mean lymphocyte count
in malignant thyroid nodule group was significantly lower than benign nodule and control groups in our study (p=0.001).
Neutrophil to lymphocyte count
ratio as an early indicator of bloodstream infection in the emergency department.
NLR was calculated by dividing absolute neutrophil count by absolute lymphocyte count
. PLR was calculated by dividing absolute platelet count by absolute lymphocyte count
The mean lymphocyte count
was significantly higher among the controls, and the mean PLR was significantly higher among the women with PTBs (Table 1).
(23) have also reported similar findings by demonstrating that a high NLR is associated with prostate carcinogenesis and concluded that inflammation associated with an increased neutrophil count and tumor response associated with a decreased lymphocyte count
might be a part of carcinogenesis.
The median lymphocyte count
of all participants was 2600 cells/[micro]L ([+ or -] 900 cells/[micro]L IQR).
With many chronic diseases, the disruption of the immune system results in a decrease in the lymphocyte count
. Lymphopenia has been documented in many diseases, such as malignancy, tuberculosis, viral infection, and peripheral vascular disease (10,11).
* NLR ratio - calculated by absolute neutrophil count divided by absolute lymphocyte count
The last three were calculated parameters where NLR is the ratio of absolute neutrophil count and absolute lymphocyte count
, LMR is the ratio of absolute lymphocyte count
and absolute monocyte count and PLR is the ratio of platelet count and absolute lymphocyte count
Recommended monitoring was according to provincial guidelines: HIV-1 RNA after 6 and 12 months on treatment and then annually if suppressed or 3-6-monthly if not suppressed, CD4+ lymphocyte count
annually until >200 cells/[micro]L, and monitoring of serum creatinine and full blood count recommended in patients on TDF and AZT, respectively.
NLR is a general inflammatory indicator that can be estimated by dividing the neutrophil count by the lymphocyte count
. NLR has been proposed as a predictive factor for different types of carcinomas, such as metastatic melanoma , esophageal cancer , colorectal cancer , non-small-cell lung cancer (NSCLC) , metastatic castration-resistant prostate cancer (mCRPC) , diffuse large B-cell lymphoma (DLBCL) , and pancreatic cancer .
NLR was calculated by dividing the absolute neutrophil count by the absolute lymphocyte count
. PLR, on the other hand, was calculated by dividing the absolute lymphocyte count
by the absolute platelet count (PLT).
The WHO recommendation that ART should commence for all HIV-confirmed individuals in clinical stages II or III with total lymphocyte count
(TLC) < 1200 cell/[micro]l was also in recognition to the challenges faced by low-resourced communities .