Biallelic inactivation of the LHCGR causes Leydig cell
hypoplasia (LCH, OMIM#238320) that leads to male disorders of sexual differentiation (DSD).
Where N(cells) is the number of the cells, V(structure) is the volume of epithelium for the cells of germinal layer, and the volume of interstitial tissue for Leydig cells
Evidence to suggest nitric oxide is an interstitial regulator of Leydig cell
Immuno-histochemical analysis showed the exclusive localization of CYP11A1 in Leydig cell
(Figure 4C, Table 3).
Dietary fats show a direct impact not only on the lipid composition of the Leydig cells
of the testes but, in turn, influence local steroidogenesis.
Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell
aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human.
One primary cause is the dysfunction of testosterone-producing Leydig cells
in the testes.
SLTC immunocytochemical characterization is positive for testosterone and estradiol of the Sertoli and Leydig cells
Tuo et al., "Characterization of Nestinpositive stem Leydig cells
as a potential source for the treatment of testicular Leydig cell
dysfunction," Cell Research, vol.
The hypothesis stated in our study is as follows: Are the seminiferous tubule structure and Leydig cell
number similar in PBS and normal fetuses?
Petty, "Leydig cell
numbers, daily sperm production, and serum gonadotropin levels in aging men," Journal of Clinical Endocrinology and Metabolism, vol.
Abney, "The potential roles of estrogens in regulating Leydig cell
development and function: a review," Steroids, vol.
Binding of thyroid hormone to goat testicular Leydig cell
induces the generation of a proteinaceous factor which stimulates androgen release.
Testis is composed of a large number of somniferous tubules which sperm is made up of its mature walls surrounding this tubules intertubular connective tissues there is interstitial cells known as Leydig cell
which secrete hormones responsible for the appearance of secondary sexual characteristics.
tumor shows tumor cells arranged in diffuse, sheet-like pattern, small nests, ribbons, and cords.