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Related to Landau-Kleffner syndrome: Prader Willi syndrome
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5-year period and failing to detect a single case of Landau-Kleffner syndrome, Dr.
Autism is a major component in tuberous sclerosis, which also results in severe cortical development problems and seizure disorder, and the Landau-Kleffner syndrome of acquired aphasia and seizure.
Even if there's a high index of suspicion for autism, a differential diagnosis should address other possible causes for the symptoms, including hearing impairment, fragile X syndrome, Rett syndrome, Landau-Kleffner syndrome, and developmental language disorder.
Furthermore, there is a rare neurological syndrome known as Landau-Kleffner Syndrome (Acquired Epileptic Aphasia) that is associated with regression of language (usually after age 36 months) and an epileptiform EEG with or without clinical seizures and thus is often confused with autistic regression.
DENVER--Routine overnight EEG testing of autistic children in an effort to identify those with treatable Landau-Kleffner syndrome is unwarranted, Dr.