After appraisal of all available data on Invirase
(sanquinavir) and the potential risk of cardiac arrhythmias its use leads to, CHMP decided that the benefits of the medicine outweigh its risks, which means that its risk-benefit profile remains positive.
The company already sells its Viracept and Invirase
drugs at no profit to Sub-Saharan African and in other countries that the United Nations defines as least developed.
Los ojos de la gente atormentada se cruzan imperceptiblemente --entra a la sala una muchacha guapa con un pantalon rosa adorablemente relleno, pero la sola idea de que este pudriendose por dentro, me hace verla con panico, como si observarla fuera una forma de contagiarme de su muerte--, y todos, tarde o temprano, terminamos leyendo los letreros en un boletin de corcho: "Vendo un frasco de Invirase
por 2 mil, Crixivan, Retrovir y HIVID por 4 mil, AZT 100 mg, Pentamidina, Videz, Fluconazol, Diadonosina, me urge".
Pls--Agenerase, Crixivan, Kaletra, Viracept, Norvir, Fortovase, Invirase
It has come to light that patients in some of the nation's correctional facilities are being treated with contraindicated anti-retroviral regimens that include the concurrent use of stavudine with zidovudine; and Invirase
with two nucleoside-analogue-reverse-transcriptase-inhibitors (NRTI).
The FDA approved the first protease inhibitor, Invirase
, in December 1995.
It is undisputed, that, for at least forty-eight to seventy-two hours, Sullivan was deprived of his medication, although PCDCC [Pierce County Detention and Corrections Center] medical officials knew that Sullivan was in the final stage of AIDS and that he was in dire need of that medication--in particular, his protease inhibitor, Invirase
," wrote judges Stephen Reinhardt, David Thompson, and Thomas Nelson.
Product insert for Invirase
(saquinavir) [Product Insert].
Saquinavir mesylate (Fortovase [soft gel capsule], Invirase
[hard gel capsule], SQV), Hoffmann-La Roche
In December 1995 the first protease inhibitor, Hoffmann-La Roche's Invirase
, was approved by the Food and Drug Administration.
Twenty-two percent were currently taking Nelfinavir and 11 percent had taken the protease inhibitor in the past; 20 percent were currently taking Crixivan and 17 percent had taken it in the past; 12 percent had taken Norvir in the past and 9 percent were currently taking Norvir; and 9 percent reported that they had taken or were now taking Invirase
In the letter, Chiang explains how high drug costs for key AIDS drugs--such as Abbott's Kaletra, BI's Aptivus, BMS' Reyataz and Genentech's Invirase
and Fuzeon--are contributing to the current ADAP crisis:
The agency said preliminary data suggest Roche Holding AG's Invirase
and Abbott Laboratories Inc.
Crixivan (indinavir), Invirase
(saquinavir), Kaletra (lopinavir/ritonavir), and Viracept (nelfinavir).
Saquinavir (SQV, Absorption increased Take with a meal: high Invirase
, the hard- with food and with fat and high calorie gel formulation) grapefruit juice.