Chronic gastritis, intestinal metaplasia, and low-grade intraepithelial neoplasia
were grouped into non-cancerous lesions; and early gastric cancer and high-grade intraepithelial neoplasia
were grouped into cancerous lesions.
Trends in vulvar neoplasia: increasing incidence of vulvar intraepithelial neoplasia
and squamous cell carcinoma of the vulva in young women.
Incidence of vaginal intraepithelial neoplasia
after hysterectomy for cervical intraepithelial neoplasia
: a retrospective study.
Histopathological analysis included diagnosis of a primary disease, but also the presence and stage of pancreatic intraepithelial neoplasia
. All slides were reviewed by two independent pathologists.
Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia
. J Natl Cancer Inst 1993;85(12):958-64.
Cervical Intraepithelial Neoplasia
(CIN) - Pipeline Products Glance 9
Squamous intraepithelial neoplasia
of the esophagus: Past, present, and future.
Twenty-five studies examined persistent CIN1 and 36 articles evaluated the progression from CIN1 to high-grade cervical intraepithelial neoplasia
and cervical cancer (CIN2+).
* The report provides a snapshot of the global therapeutic landscape of Cervical Intraepithelial Neoplasia
Abnormal cervical cell growth--called cervical dysplasia or cervical intraepithelial neoplasia
(CIN)--develops before cervical cancer and can lead to cervical cancer.
A study of accuracy of colposcopic grading for detection of high-grade cervical intraepithelial neoplasia
concluded that finding of acetowhite lesions identify the women with CIN2+, and biopsy of all these lesions maximises the sensitivity and specificity of colposcopic diagnosis.8 A study conducted in India found colposcopy a good sensitive test for detection of CIN with sensitivity up to 74.7% and specificity up to 92.9%.
The 3%-5% of all tested cases are classified as ASCUS (Atypical Squamous Cells of Undetermined Significance) and another 3%-5% are reported as low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL) or cervical intraepithelial neoplasia
Ninety-seven men with high-grade prostatic intraepithelial neoplasia
and/or atypical small acinar proliferation were given capsules containing green tea catechins or a placebo for one year.
Quadrivalent human papilil lomavirus (qHPV) vaccine reduces rates of anal intraepithelial neoplasia
(AIN) by 50% to 54%, and persistent anal infection by 59%, associated with the 4 types of HPV in the vaccine (6, 11, 16, and 18) in young men who have sex with men (MSM); it also reduces external genital lesions by 66%, and persistent HPV infection associated with the same 4 HPV types by 48 to 59% in all young men, heterosexual men, and MSM (strength of recommendation [SOR]: B, randomized, placebo-controlled trials [RCTs]).
It covers human papillomavirus (HPV) carcinogenesis and the natural history of cervical cancer, primary prevention through HPV vaccination, pap smear screenings, the practical aspects of smear taking, the management of abnormal pap smears, the approach to population-based screening, visual screening tests, the role of HPV detection in cervical cancer screening, the basics of colposcopy, the detection of cervical neoplasia through a colposcope, problems in colposcopy, and the management of cervical intraepithelial neoplasia
, including ablative methods for treatment and excisional therapy.