Direct control of hepatic glucose production by interleukin-13
Egan et al., "Autocrine role of interleukin-13
on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7," American Journal of Physiology Endocrinology and Metabolism, vol.
Matteucci et al., "Regulation of endothelial and mesothelial cell function by interleukin-13
: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production," Blood, vol.
Ichimura et al., "Interleukin-13
gene polymorphisms confer the susceptibility of Japanese populations to Graves' disease," Journal of Clinical Endocrinology and Metabolism, vol.
Some of these changes involved "a protein called interleukin-13
and related intracellular signaling mechanisms," he stated.
Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13
via the signal transducer and activator of transcription 6.
Pulmonary expression of interleukin-13
causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.
We have specifically added a number of markers of inflammation [C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1 (IL-1), interleukin-13
(IL-13) and tumornecrosis factor alpha (TNF-a)] in our projects that are tracking uric acid through treatment with allopurinol.
Gp120 is thought to act as a superantigen, stimulating the immune system with a bias toward Th2 cytokine production via release of IL-4 and interleukin-13
(IL-13) from human F epsilon R-positive cells ([F.sub.c[epsilon] R1+ cells).
Elevated levels of interleukin-13
and IL-18 in patients with dengue hemorrhagic fever.
Heska Corporation (Loveland, CO) has patented canine immunoglobulin G (IgG) and canine interleukin-13
receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R.
Results are showing that both allergens produce significant increases in inflammation-related white blood cells in the lungs of the mice, and they elevate blood levels of key markers of allergic reactions, including IgE, interleukin-5, and interleukin-13
. Mice not treated with antibiotics show much milder reactions to the allergens.
We have previously used this approach to determine the cis/trans chromosomal orientation of the individual nucleotides in SNPs located in the interleukin-13
gene and, thus, the specific allelic haplotypes of that gene (10).
Malignant glioma cells, as compared to normal brain cells, express interleukin-13
(IL13) receptors at a high density.
According to the companies, Dupixent is a fully-human monoclonal antibody that inhibits the signaling of interleukin-4 (IL-4) and interleukin-13
(IL-13), two proteins that play a central role in type 2 inflammation.