We demonstrated that clinical manifestation of hyperbilirubinaemia
patients was more serious, C3 levels were significantly lower in hyperbilirubinaemia
patients, and lower C3 levels were closely correlated with liver injury and impaired liver regeneration.
Apart from causing neonatal deaths and chronic handicapping conditions such as cerebral palsy, severe unconjugated hyperbilirubinaemia
usually causes deafness, speech disorders, learning disabilities and mental retardation.
26-28] RIF may occasionally cause dose-dependent interference with bilirubin uptake, resulting in subclinical, unconjugated hyperbilirubinaemia
or jaundice without hepatocellular damage.
The influence of hyperbilirubinaemia
on malaria-related mortality: An analysis of 1103 patients.
Lantana toxicity is manifested in three phases-release and absorption of toxins in the gastrointestinal tract, hepatic phase (cholestasis, hyperbilirubinaemia
, hyperphyllo-erythrinaemia) and the tissue phase wherein cell injury results from accumulation of bilirubin and phylloerythrin (Sharma et al.
Prediction of severe hyperbilirubinaemia
using the Bilicheck transcutaneous bilirubinometer.
Yellow discolouration of skin and whites of the eye (sclera) * Hyperbilirubinaemia
occurs in 1 in 2 000 obstetric patients.
7-9 Bilirubin may be elevated in conditions which lead to liver cell damage and cholestasis, such as hemolysis, hepatitis, drugs, chemotherapy, biliary stricture, neonatal hyperbilirubinaemia
and Gilbert's syndrome.
Relationship between hyperbilirubinaemia
and UDP-glucuronosyltransferase 1A1 polymorphism in adult HIV-infected Thai patients treated with indinavir.
Serum malondialdehyde concentration in babies with hyperbilirubinaemia
Detection of sensorineural hearing loss using automated auditory brainstem-evoked response and transientevoked otoacoustic emission in term neonates with severe hyperbilirubinaemia
On the other hand, hyperbilirubinaemia
is often the first and sometimes the only manifestation of liver disease.
Infant outcomes consisted of preterm birth (<37 completed weeks of gestation), extreme-to-moderate preterm birth (<34 completed weeks of gestation), low birthweight (<2,500 g), very low birthweight (<1,500 g), intrauterine/foetal growth restriction (IUGR), and 'perinatal' comprising birth asphyxia (indexed by Apgar scores of <7 at one minute and five minutes), suspected neonatal sepsis (used collectively for septicaemia, meningitis, and pneumonia), and hyperbilirubinaemia
Premature babies: acidosis, apnea, bradycardia, cold stress, hyperbilirubinaemia
, hypocalcaemia, hypoglycaemia pneumonia, respiratory distress syndrome, convulsions, sepsis, apnea, stress cooling.