The initiatives include growing the core business, development of humanized antibodies
, expansion through an M&A strategy, and investing in acquisition and development of intellectual property assets.
Protein Design is a leader in the development of humanized antibodies
to prevent or treat various disease conditions.
IMUC will retain all rights to the humanized antibodies
and will explore partnering opportunities with companies that may be interested in small cell lung, pancreatic and colon cancer targeting opportunities as we continue to seek the fastest path to FDA approval for these potentially revolutionary therapies," concluded Dr.
Fremont, CA; 510-574-1419) announced that it has granted a non-exclusive license under its antibody humanization patents to Celltech for humanized antibodies
against tumor necrosis factor-alpha, believed to be an important factor in the inflammatory process in humans.
Improved anti-CD20 antibodies aim at reducing immunogenicity and the related side effects (infusion and anaphylactic reactions) by fully human or humanized antibodies
Forty additional humanized antibodies
are in clinical trials.
a leading company in the development of humanized antibodies
Protein Design has granted licenses under its antibody humanization patents for each of the three currently marketed humanized antibodies
For human medicine, cloning may be used to develop animals that secrete therapeutic proteins in their milk to produce humanized antibodies
for use as vaccines or generate animal tissues modified for xenotransplantation.
Overall, Protein Design has entered into agreements with numerous pharmaceutical and biotechnology companies for exclusive or non-exclusive rights under its antibody humanization patents covering more than 40 humanized antibodies
, over half of which are in clinical development.
The contract with Cytovance represents a major step forward for Selexys as we move our portfolio of engineered humanized antibodies
towards clinical development," said Richard Alvarez, chief operating officer of Selexys.
Merck is the twenty-eighth company to have signed an agreement with Protein Design related to humanized antibodies
and our antibody humanization patents," said Robert L.