The team looked at two forms of the hormone therapy
- one oral estrogen (conjugated equine estrogen) and a patch (17 beta-estradiol) - to find out how their use affected sleep quality.
Authors noted that the retrospective studies may be influenced by recall bias and selection bias, and that the median year of diagnosis in the retrospective studies was in 1992, well before peak hormone therapy
Key clinical point: Menopausal hormone therapy
is associated with an increased risk of major gastrointestinal bleeding, particularly in the lower gastrointestinal tract.
The recruits were due for a screening mammography, and reported on use of hormone therapy
for 2 years.
WHI has made an important contribution by changing the clinical practice of starting hormone therapy
in older women at higher risk of heart disease, Dr.
The fact that there were so many people using, and then abandoning, hormone therapy
makes this into a sort of large-scale natural experiment.
The findings are part of a study that found that a group of postmenopausal women showed more brain activity during a visual memory test than did women who were not taking the hormone therapy
Based on their review of these studies, the authors summarize "what we know" and "what we do not know" about the effects of hormone therapy
on the sexual function of postmenopausal women.
Isaac Schiff of Massachusetts General Hospital, told doctors last month that it was time for a balanced, analytical debate on hormone therapy
We are confident that the WHI findings, if objectively assessed and incorporated, have given physicians and their patients reasons to reconsider alternative and equally effective methods of postmenopausal hormone therapy
That's when researchers abruptly halted part of the Women's Health Initiative (WHI), a major federally funded clinical study to assess the effect of long-term use of hormone therapy
In the 6-8 months after publication of findings from the Women's Health Initiative on the risks associated with postmenopausal hormone therapy
, more than half of women in a large California health plan who had been regularly using hormone therapy
tried to stop, even though two-thirds overall did not know what the study's main findings were, according to a survey of female members of the plan.
The initiative comes almost six months after Congress directed the agency to develop the program that targets women through partnerships with organizations across the country after a January 2003 report from the Women's Health Initiative linked hormone therapy
with an increased risk of coronary disease, heart attacks, breast cancer and other ailments.
The type of progestin hormone used in menopausal hormone therapy
may have a large influence on the safety and potential side effects of that therapy, says Regine Sitruk-Ware, Population Council executive director for product research and development.
A SHORT COURSE of hormone therapy
appears to increase muscle strength in men over age 60, USC researchers have found.