haplotype

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  • noun

Words related to haplotype

(genetics) a combination of alleles (for different genes) that are located closely together on the same chromosome and that tend to be inherited together

References in periodicals archive ?
In order to analyze the most common PTGS2 haplotypes, different PR and 3'-UTR variants were generated by site-directed mutagenesis using overlap extension PCR (14).
To change this, we are excited to collaborate with 10x Genomics to incorporate haplotype genomic information into the next generation of NIPT, said Dr.
Attributions of haplotypes as native were based on the analysis of historical museum specimens from throughout the historical range of the Red Fox in North America by Aubry and others (2009).
Blue arrow denotes a highly connected basal haplotype from which nearly all haplotypes originated.
Human leukocyte antigen (HLA) loci including HLA-A, -B, -C, -DR, -DQ, and -DP individually along with HLA haplotypes which are comprised HLA loci as a DNA string on one chromosome have been found to be associated with many diseases with autoimmune disorders, such as ankylosing spondylitis (AS),[sup][1],[2] type 1 diabetes,[sup][3],[4],[5],[6],[7],[8],[9] inflammatory bowel disease,[sup][10],[11],[12] with strong association between HLA-B27 and AS being the typical example.
2014) identified two haplotypes from seven juveniles found in Colombian Pacific waters.
The Greek Cypriots' haplotypes were then compared to a publicly available Turkish Cypriot population sample as well as profiles from populations in West Eurasia and North Africa.
com) was used to produce minimum spanning networks of all haplotypes with the Median Joining calculation (Bandelt et al.
The relative haplotype dosage (RHDO) [7] approach, on the other hand, allows the deduction of the fetal genotype by measuring the relative counts of single nucleotide polymorphism (SNP) alleles on haplotypes linked with the mutant allele and wild-type allele in maternal plasma DNA (13).
The combination of the five mutations in the MC1R gene resulted in eight different haplotypes deposited in GenBank under the accession numbers KU705368-KU705368 (Table 3).
These haplotypes were compared in phylogenetic trees with 347 additional mtDNA D-loop sequences already reported for river and swamp buffaloes.
Determining which HLA alleles and haplotypes are present in well-defined populations (and their frequencies) has practical applications, including calculating the probability of finding a suitable HLA-matched donor for a recipient.
Domestic cats carry seven different versions, or haplotypes, of this protein, called APOBEC3Z3.