We used Pearson's correlation analysis to test the correlation between TC, TG, HDL
, LDL and the ratios of TC/HDL and LDL/HDL.
It's true that people with very low HDL
People with HDL
cholesterol levels greater than 60 mg/dl had a nearly 50 per cent increased risk of dying from a cardiovascular cause or having a heart attack compared to those with HDL
cholesterol levels 41-60 mg/dl.
"We have been seeing an unexpected relationship between HDL
cholesterol and postmenopausal women in previous studies, but have never deeply explored it," notes El Khoudary.
In this issue of Clinical Chemistry, investigators from the Boston Heart Diagnostics group report a comparison of their HDL
mapping method with 4 different clinical methods for HDL
Measurement of Vitamin E ([alpha]-Tocopherol) in HDL
from 81 diabetic patients was purified by density gradient microultracentrifugation as described above.
The latest disappointment he reported was in CER-001, an engineered HDL
Nicholls, MD, a long-time leader in the field who has reported results from a series of studies during the past 10 or so years that tested various approaches to juicing HDL
cholesterol activity in patients, only to see each and every candidate intervention result in an inability to budge clinical outcomes.
HDL-C takes an anti-atherosclerotic role by the reverse transport of cholesterol from the peripheral tissues.[sup] Moreover, HDL-C may possess antioxidant and anti-inflammatory actions [sup] and inhibit the cytokine-induced expression of endothelial cell adhesion molecules, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1.[sup] In addition, HDL
can inhibit thrombus formation.[sup] HDL-C particles include many surface proteins and lipids that influence the function of HDL
and may provide atheroprotection via favorable effects upon atherosclerotic mechanisms, including modulation of inflammation, oxidation, endothelial function, and insulin secretory capacity.
TEHRAN (FNA)- Commonly touted as "good cholesterol" for helping to reduce risk of stroke and heart attack, both high and low levels of high-density lipoprotein (HDL
) cholesterol may increase a person's risk of premature death, according to new research.
High density lipoprotein (HDL
) has long been thought of as bene-ficial because of the way it transports harmful substances away from artery walls.
FBS was estimated by GOD-PAP method, TC by CHOD-POD method, TG by GPO peroxidase method and HDL
was estimated by direct determination using enzyme selective protection method.
is a heterogeneous particle with a density of 1.063-1.21 gm/ml showing a complex function of its role in heart diseases.
On comparison of fasting lipid profile, TC/HDL ratio and TG/HDL ratio, it was observed that the average total cholesterol, HDL
cholesterol, TCL/HDL ratio were insignificant.