antigen

(redirected from HBcAg)
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Related to HBcAg: anti-HBc, HBcAb, HBeAg, HBsAg
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  • noun

Words related to antigen

any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

References in periodicals archive ?
Failure in the HBcAg assembly might then cause excessive accumulation of viral capsids within hepatocytes.
As shown in Figure 1 for EpCAM staining, CSCs were abundant throughout the HCC and coexpressed both HBcAg (panel (a)) and HBx (panel (b)).
The baboons were serologically negative, and the 1 baboon examined histologically had mild focal lobular hepatitis, and HBcAg was detected in liver tissue by immunohistochemical staining.
En terminos generales los sistemas NAT pueden constituir un avance significativo en la automatizacion de los bancos de sangre y aumentan la seguridad de los pacientes que reciben sangre donada, aunque la combinacion con la determinacion de los antigenos HBsAg y HBcAg seria la ideal para un correcto tamizaje (22, 23).
Antibodies to the core antigens (HBcAg) do not confer immunity (Bader, 1996).
TABLE 1 Hepatitis Nomenclature and Other Terminology HBV Hepatitis B virus HBsAg Hepatitis B surface antigen HBeAg Hepatitis B e antigen HBcAg Hepatitis B core antigen Anti-HBs Antibody to HBsAg Anti-HBe Antibody to HBeAg Anti-HBc Antibody to HBcAg IgM anti-HBc IgM class antibody to HBcAg IgG anti-HBc IgG class antibody to HBcAg HBIG Hepatitis B immune globulin
The bulk of amino acids are shared with HBcAg, but HBeAg posseses an N-terminal extension of 10 amino acids and a C-terminal truncation of 34 amino acid residues.
A liver biopsy was obtained at exacerbation, when possible, for staging fibrosis, grade of necroinflammatory activity, and detection of HBcAg in tissue.
Monoclonal goat-anti-human HBsAg and HBcAg antibodies were purchased from Dako (Denmark), and immunohistochemical staining for HBsAg and HBcAg in renal biopsies was used to confirm the diagnosis.
Although antibody associated mechanisms targeting hepatitis B core antigen (HBcAg) was reported in earlier studies, few data exist on B lymphocytes population in the liver of patients with CHB.
A study by Chan Y et al revealed that effectively treated patients showed increased frequency of peripheral blood CD4 (+) T Lymphocytes, an augmented proliferative response of HBV specific T cells to Hepatitis B Core antigen (HBcAg) and the induction of cytokines such as interferon gamma (IFN-g), Tumour Necrosis Factor alpha (TNF- alpha) release at the site of infection compared to non-responsive patients.
A study by Chan et al revealed that effectively treated patients showed increased frequency of peripheral blood CD4(+) T Lymphocytes, an augmented proliferative response of HBV specific T-cells to the Hepatitis B Core antigen (HBcAg), and the induction of cytokines such as gamma interferon (IFN-a), tumour necrosis factor alpha (TNF a) release at the site of infection compared to non responsive patients.17
We detected antibodies against hepatitis B core antigen (HBcAg) by using AxSYM (Abbott, Montreal, Quebec, Canada) and analyzed data by using Stata 10.0 (StataCorp LP, College Station, TX, USA).
Se ha demostrado que el HBeAg puede promover la cronicidad, por funcionar como una proteina inmunoreguladora (161), probado en ratones transgenicos que posterior a la transferencia transplacentaria de HBeAg materno, desarrollan respuesta tolerogenica e inactivacion de respuesta T ayudadora HBeAg/ HBcAg especifica a traves de eliminacion clonal central, anergia e ignorancia clonal, resultante en una respuesta citotoxica ineficiente.