Examining medical data acquired from July 2002 to June 2004, the researchers identified 157,625 people- mostly Caucasian men ages 65 and older- who had been newly prescribed PPIs, and 56,842 people who had been newly prescribed another class of acid-suppression drugs known as H2 blockers
. They followed the patients- 214,467 in total- for up to 10 years.
After initiation of PPI daily, an H2 blocker
before bedtime, a low-acid diet, and alkaline water, the patient was found to have a decrease in his reflux finding score from 11 to 6, and his granuloma resolved without surgery.
Prokinetic activity of H2 blockers
is believed to be a consequence of acetylcholinesterase (AchE) inhibition, the enzyme that degrades acetylcholine (Ach) in the synaptic cleft.
Boustani said earlier studies have linked another type of antacid, H2 blockers
, with an increased risk of dementia.
(7,8) it has been found that H2 blockers
are not protective against NSAIDs-induced gastric irritation which also favors the same.
"Our results demonstrate that PPIs appear to be associated with elevated risk of heart attack in the general population, and H2 blockers
show no such association."
If I had an endoscopy and it didn't really show anything, I would take that to mean that I have a mild problem and that occasional treatment with antacids or an occasional H2 blocker
would work for me.
If these aren't sufficient, your doctor may recommend a proton pump inhibitor (PPI) such as omeprazole (Prilosec[R]), lansoprazole (Prevacid[R]), and esomeprazole (Nexium[R]); or an H2 blocker
such as famotidine (Pepcid[R]), Cimetidine (Tagamet[R]), and ranitidine (Zantac[R]).
She had been working with the voice team, and her reflux was controlled with a proton-pump inhibitor and an H2 blocker
. Because strobovideolaryngoscopy revealed greater-than-expected stiffness of the right vocal fold, an in-office peroral vocal fold injection with dexamethasone was offered to the patient.
People who took an H2 blocker
had no greater risk than non-users.
For patients with minor or occasional GERD symptoms, antacids or an H2 blocker
Patients with history of use of Steroid, NSAIDS and who had taken PPI or H2 Blocker
within two weeks.
"There are gastrointestinal risks, and for some patients, particularly those taking concurrent aspirin, they may need to take medication to protect their gastrointestinal tract, such as a proton pump inhibitor or an H2 blocker
In addition to lifestyle changes, a trial of acid-suppressing medication, such as an H2 blocker
or a proton pump inhibitor, can be tried.
In addition, 34% were taking a proton-pump inhibitor or an H2 blocker
. Those percentages were higher than the percentages in the control patients in the study, funded by Tap Pharmaceuticals.