Similarly, no pathogenic variants were detected in GJA1, suggesting their non-implication in hearing loss among the Cameroonians and black South Africans studied,  as has been reported in African Americans.
From our analysis, there is no evidence that mutations in GJB2, GJB6 or GJA1 are associated with non-syndromic deafness in sub-Saharan African patients.
Mutations in GJA1 (connexin 43) are associated with non-syndromic autosomal recessive deafness.
In search of genetic markers for nonsyndromic deafness in Africa: A study in Cameroonians and black South Africans with the GJB6 and GJA1 candidate genes.
Jason Bosch completed his MSc in human genetics on the project, with molecular analysis of the GJB2 and GJA1 genes, and Kamogelo Lebeko did all the experiments on the GJB6 gene for her honours degree in human genetics.