Trakya'da riskli bir bolgede tularemi insidansinin ve dere/sebeke sularinda Francisella tularensis
has signed a license agreement with the National Research Council (NRC) of Canada to develop ATI-1701, a vaccine to protect against Francisella tularensis
, a potential bioterrorism agent that causes tularemia, the company said.
The causative agent Francisella tularensis
has been classified as a Category A bioterrorism agent by the CDC.
Frelinger, "Respiratory Francisella tularensis
live vaccine strain infection induces Th17 cells and prostaglandin E2, which inhibits generation of gamma interferon-positive T cells," Infection and Immunity, vol.
Cardile, "Continued safety and immunogenicity study of a live Francisella tularensis
vaccine," May 2016, https:// clinicaltrials.gov2016.
The report by NTI also stated North Korea was capable of indigenously producing other agents of biological warfare including Variola major (smallpox), Francisella tularensis
(rabbit fever), and Bunyaviridae Hantavirus (Korean hemorrhagic fever).
(FT) is a Tier 1 select agent due to its low infectious dose and potential threat of being a bio-weapon while causing zoonotic disease in more than 150 mammalian species.
On June 15, 2016, Arizona public health officials were notified of a presumptive positive Francisella tularensis
blood culture result from a woman aged 73 years with pulmonary sarcoidosis who had recently died from respiratory failure.
Project 3 Novel Essential Target: The talk will explore how a series of novel oxadiazoles bind to a unique site on the ribosome, resulting in potent inhibition of the essential non-stop ribosome rescue pathway in Gram-positive and negative pathogens, including MDR Neisseria gonorrhoeae and Francisella tularensis
. These compounds exhibited potent antibacterial activity and oral bioavailability.
The described approach amplified target sequences specific to Yersiniapestis, Francisella tularensis
Tularemia is a zoonotic disease caused by the gram-negative bacteria Francisella tularensis
and is seen in the northern hemisphere (1).
For instance, due to the risk of deliberate misuse and potential for mass casualties or devastating effects to the economy, critical infrastructure, or public confidence, the CDC has classified Francisella tularensis
and Burkholderia pseudomallei as Tier 1 select agents.
Tularemia caused by Francisella tularensis
, an intracellular obligate aerobic gram-negative coccobacillus, is a zoonosis with natural focality distributed in geographical regions of the Northern hemisphere.
Tularemia jest wielopostaciowa, ostra zoonoza wywolywana przez paleczki z gatunku Francisella tularensis
. Na obszarze Polski czynnikiem etiologicznym jest podgatunek Francisella tularensis
[USPRwire, Tue Oct 06 2015] Global Markets Direct's, 'Francisella Tularensis
Infections - Pipeline Review, H2 2015', provides an overview of the Francisella Tularensis
Infections's therapeutic pipeline.